ACTIVATE: A Computerized Training Program for Children With ADHD

In an open clinical trial, ACTIVATE, a computer-based neurocognitive intervention will be
evaluated to determine its effectiveness in improving symptoms of
attention-deficit/hyperactivity disorder (ADHD) and related impairments. ACTIVATE is a
computerized neurocognitive training program (ACTIVATE; see: www.c8sciences.com) that
simultaneously targets eight core neurocognitive factors (i.e., sustained attention, working
memory (WM), response inhibition, speed of information processing, cognitive flexibility and
control, multiple simultaneous attention, category formation, and pattern recognition and
inductive thinking). Youth between the ages of 7-11 will be recruited and assessed for ADHD
and assigned to the ACTIVATE intervention. Assessment of outcomes will occur before, weekly
during treatment, and immediately post-treatment.

Inclusion Criteria:

- Children ages 7-11 with a diagnosis of ADHD

- Parent and child must be fluent English speakers

- Family has access to desktop/laptop computer at home with internet access (in order to
implement the ACTIVATE intervention component, which is an online-based computer
program)

Exclusion Criteria:

- Developmental delay or psychosis that impacts the child's ability to function and
engage in the computerized intervention

- If the youth or parent presents with emergency psychiatric needs that require services
beyond that which can be managed within a preventive intervention format (e.g.
hospitalization, specialized placement outside the home)

- If the child has an estimated Full Scale IQ below 80, based on completing two subtests
of the Wechsler Intelligence Scale for Children - Fourth Edition