Cannabidiol Oral Solution as an Adjunctive Treatment for Treatment-resistant Seizure Disorder

Inclusion Criteria:

- Completed activities through Day 11 in INS011-14-029 or Part A (Visit 6) INS011-15-054

- Informed consent/assent (as applicable) was voluntarily provided by the participant
and/or parent(s)/caregiver(s) in accordance with applicable laws, regulations, and
local requirements

- Is medically stable with no anticipated changes in chronic medications in the opinion
of the Investigator

- Continues to meet protocol-specified criteria for qualification and contraception,
including treatment-resistant seizure disorder

- In the opinion of the Investigator, the subject and/or parent(s)/caregiver(s) are able
to continue keeping accurate seizure diaries

Exclusion Criteria:

- Inadequate supervision by parent(s)/caregiver(s)

- History or current use of dietary supplements, drugs or over-the counter medications
outside protocol-specified parameters

- Signs, symptoms or history of any condition that, per protocol or in the opinion of
the investigator, might compromise:

1. the safety or well-being of the participant or study staff

2. the safety or well-being of the participant's offspring (such as through
pregnancy or breast-feeding)

3. the analysis of results