Feasibility of Short Breast MRI (SBMRI) for Screening Patients at High Risk for Breast Cancer

If you agree to take part in this study, you will have the short breast MRI scan (the scan
for research purposes) with contrast on a different day than your scheduled routine MRI
screening scan with contrast. You will have your routine scan the first day and the research
scan at least 1 day after. The research scan will take about 10 minutes to complete.

After your short breast MRI scan is completed, you will complete a questionnaire about your
comfort level and experience of the research scan. It should take about 10 minutes to
complete the questionnaire.

This is an investigational study. The short breast MRI is considered investigational.

Up to 200 participants will be enrolled in this study. All will be enrolled at MD Anderson.

Inclusion Criteria:

1. 18 years and older female patients

2. BMRI indication: high risk screening per ACS guidelines

3. No contraindications to undergo MRI

4. Creatinine 40

5. No requirement for sedation.

Exclusion Criteria:

1. <18 years

2. Male

3. Is pregnant (confirmed by the patient as Imaging Clinic standard of care) or nursing
mother

4. Contraindication to Gd contrast agents

5. Previous documented history of moderate to severe hypersensitivity to Gd contrast
agents

6. Contraindications to MRI