Double-Blind Efficacy and Safety of CD5789 (Trifarotene) 50µg/g Cream Versus Vehicle Cream in Acne Vulgaris

Inclusion Criteria:

- The subject is a male or female, 9 years of age or older, at Screening visit.

- The Subject has moderate acne at Screening and Baseline.

- The subject is a female of non childbearing potential

- The subject is a female of childbearing potential with a negative pregnancy test and
who is strictly abstinent or who agrees to use an effective and approved contraceptive
method for the duration of the study and at least 1 month after the last study drug
application.

Exclusion Criteria:

- The subject has severe forms of acne (e.g., acne conglobate, acne fulminant) or
secondary acne form (e.g.,chloracne, drug-induced acne, etc.).

- The subject has any uncontrolled or serious disease or any medical or surgical
condition that may either interfere with the interpretation of the trial results
and/or put the subject at significant risk (according to the Investigator's judgment)
if the subject takes part to the trial.

- The subject has been exposed to excessive ultraviolet (UV) radiation within one month
prior to the Baseline visit or the subject is planning intense UV exposure during the
study (i.e., occupational exposure to the sun, sunbathing, tanning salon use,
phototherapy, etc.)

- The subject is unwilling to refrain from use of prohibited medication during the
clinical trial