A Study of the Concurrent Use of AGN-190584 and AGN-199201 in Participants With Presbyopia

Status:	Completed
Conditions:	Ocular
Therapuetic Areas:	Ophthalmology
Healthy:	No
Age Range:	40 - 50
Updated:	10/20/2018
Start Date:	April 29, 2016
End Date:	October 18, 2017

A Phase 2, Multicenter, Double-masked, Randomized, Vehicle-Controlled, Study of the Concurrent Use of AGN-190584 and AGN-199201 in Patients With Presbyopia

This study will identify the optimum concentrations of AGN-199201 and AGN-190584 when dosed
in combination once a day for the improvement of uncorrected near visual acuity in
participants with presbyopia (inability to focus on items close-up).

Inclusion Criteria:

-Normal vision at distance, either natural or post corneal laser refractive surgery, with
presbyopia in each eye and complaints of poor near vision that impacts activities of daily
living.

Exclusion Criteria:

- Use of any topical ophthalmic medications, including artificial tears other than the
study medications during the study

- Corneal abnormalities in either eye that interfere with visual acuity

- History of cataract surgery, phakic intraocular lens surgery, corneal inlay surgery or
any intraocular surgery

- Diagnosis of glaucoma or ocular hypertension.

We found this trial at

sites

Milton M. Hom, OD, FAAO

Azusa, California 91702

from

Azusa, CA