A Study of the Concurrent Use of AGN-190584 and AGN-199201 in Participants With Presbyopia



Status:Completed
Conditions:Ocular
Therapuetic Areas:Ophthalmology
Healthy:No
Age Range:40 - 50
Updated:10/20/2018
Start Date:April 29, 2016
End Date:October 18, 2017

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Trial Summary
Trial Overview
Inclusion Criteria

A Phase 2, Multicenter, Double-masked, Randomized, Vehicle-Controlled, Study of the Concurrent Use of AGN-190584 and AGN-199201 in Patients With Presbyopia

This study will identify the optimum concentrations of AGN-199201 and AGN-190584 when dosed
in combination once a day for the improvement of uncorrected near visual acuity in
participants with presbyopia (inability to focus on items close-up).


Inclusion Criteria:

-Normal vision at distance, either natural or post corneal laser refractive surgery, with
presbyopia in each eye and complaints of poor near vision that impacts activities of daily
living.

Exclusion Criteria:

- Use of any topical ophthalmic medications, including artificial tears other than the
study medications during the study

- Corneal abnormalities in either eye that interfere with visual acuity

- History of cataract surgery, phakic intraocular lens surgery, corneal inlay surgery or
any intraocular surgery

- Diagnosis of glaucoma or ocular hypertension.
We found this trial at
20
sites
West Coast Eye Care
6945 El Cajon Boulevard
San Diego, California 92115
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San Diego, CA
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Sall Research Medical Center, Inc.
Artesia, California 90701
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Artesia, CA
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Milton M. Hom, OD, FAAO
Azusa, California 91702
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Azusa, CA
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Specialized Eye Care
1 Village Square
Baltimore, Maryland 21210
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Baltimore, MD
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Cleveland Eye Clinic
Brecksville, Ohio 44141
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Brecksville, OH
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WCCT Global, LLC
Costa Mesa, California 92626
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Costa Mesa, CA
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Scott & Christie and Associates, PC
Cranberry Township, Pennsylvania 16066
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Cranberry Township, PA
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Hoopes Durrie Rivera Research, LLC
Draper, Utah 84020
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from
Draper, UT
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Cataract & Glaucoma Center
El Paso, Texas 79902
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from
El Paso, TX
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Price Vision Group
Indianapolis, Indiana 46260
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mi
from
Indianapolis, IN
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Eye Centers of Racine and Kenosha
Kenosha, Wisconsin 53142
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mi
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Kenosha, WI
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Corneal Consultants of Colorado, P.C
Littleton, Colorado
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mi
from
Littleton, CO
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Total Eye Care, PA
Memphis, Tennessee
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mi
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Memphis, TN
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Clayton Eye Center
Morrow, Georgia 30260
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mi
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Morrow, GA
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Mid Florida Eye Center
Mount Dora, Florida 32757
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mi
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Mount Dora, FL
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Eye Research Foundation
Newport Beach, California
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Newport Beach, CA
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North Bay Eye Associates
Petaluma, California 94954
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Petaluma, CA
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Martel Eye Medical Group
Rancho Cordova, California 95670
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mi
from
Rancho Cordova, CA
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Medical Center Ophthalmology Associates
San Antonio, Texas 78240
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mi
from
San Antonio, TX
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Comprehensive Eye Care Ltd
Washington, Missouri
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mi
from
Washington, MO
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