One Week Aligner Evaluation

The Invisalign® System consists of a series of clear plastic aligners that are intended to
replace conventional wire and bracket technology for many orthodontic cases. Each custom
manufactured aligner exerts gentle, continuous forces to move teeth incrementally from their
original state to a final, treated state. The aligners are designed to optimally move each
tooth at a speed that follows physiologic principles. The purpose of this study is to
demonstrate that changing aligners weekly provides similar results to changing aligners every
two weeks.

Inclusion Criteria:

- Subject must have fully erupted dentition except for 2nd and 3rd molars

- For Teen treatment group, subjects ages <17 years of age

- For Adult treatment group, subjects ≥17 years of age

Exclusion Criteria:

- Subject has undergone any accelerated orthodontic treatment prior to or during
treatment as part of this study

- Subject with active caries

- Subject with periodontal disease

- Subject with TMD symptoms

- Subject has known allergy to latex or plastic

- Subjects who are pregnant or will become pregnant during treatment