Prospective Randomized Comparison of Zymar(Gatifloxacin) and Vigamox (Moxifloxacin) in Killing Conjunctival Bacterial Flora Following a One-Hour Application



Status:Recruiting
Healthy:No
Age Range:50 - Any
Updated:5/27/2013
Start Date:April 2007
Contact:Miri Englander, BA
Email:MiriMD@Stanford.edu
Phone:650 804 8408

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Prospective Randomized Comparison of Zymar(Gatifloxacin) and Vigamox (Moxifloxacin) in Killing Conjunctival Bacterial Flora Following a One-Hour


Topical ophthalmic antibiotics are common prescribed just prior to eye surgery to lower the
risk of infection. Previous studies have suggested that antibiotics containing a
preservative (Zymar) kill bacteria much quicker than those without a preservative (Vigamox).
The purpose of this research is to compare how quickly to the two commonly prescribed
antibiotics eliminate bacteria from the eye surface.


Inclusion Criteria:

- Age- older than 50 years of age

- Diagnosis- Cataract or had cataract surgery

Exclusion Criteria:

- Systemic or topical antibiotic treatment within 30 days

- Use of systemic or topical steroids

- Active ocular infection

- Ocular surgery in the past 6 months

- Allergy to fluoroquinolones
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Stanford, California 94305
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