Motivated Behavior in Adults With and Without ADHD

Inclusion Criteria:

1. generally healthy

2. between the ages of 18-45

3. non-ADHD subjects do not meet criteria for ADHD diagnosis or any subtype as determined
by the Conners Diagnostic Interview or any T-Score > 55 on Inattentive Symptoms,
Hyperactive-Impulsive Symptoms, Total Symptoms or ADHD Index subscales of the CAARS.

4. ADHD subjects meet criteria for a primary diagnosis of ADHD, any subtype, based on
DSM-5

Exclusion Criteria:

1. inability to attend all required experimental sessions

2. significant health problems (e.g., current and uncontrolled liver, lung, or heart
problems, current or past seizure disorder, serious head trauma)

3. primary diagnosis of Axis I psychiatric disorders other than ADHD (e.g., depression,
anxiety disorder, schizophrenia)

4. meet DSM-5 criteria for substance use disorder other than nicotine in the past 12
months

5. use of psychoactive medications in the past 6 months as indicated by self-report

6. positive urine drug screen for drugs or positive breath alcohol concentration

7. contraindications for MPH

8. among women, nursing or a positive pregnancy test

9. IQ < 80 on Kaufman Brief Intelligence Test, 2nd edition

10. allergy to lactose

11. hypertension (If subject is ≤ 40 years of age and has blood pressure over 135/85 or
heart rate over 90 beats per minute. If subject is > 40 years of age and has blood
pressure over 130/80 or heart rate over 88 beats per minute)

12. body mass ratio > 30