Timolol Eye Drops in the Treatment of Acute Migraine Headache



Status:Completed
Conditions:Migraine Headaches, Migraine Headaches
Therapuetic Areas:Neurology
Healthy:No
Age Range:18 - Any
Updated:4/26/2018
Start Date:January 2016
End Date:August 1, 2017

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The goal of this study is to determine whether timolol eye drops are effective in alleviating
acute migraine headaches. Subjects will be randomized to receive either timolol eye drops or
placebo (tears) to use as a migraine abortive medication.


Inclusion Criteria:

- Diagnosis of migraine headache

Exclusion Criteria

- Non-migraine headache

- Use of systemic beta-blocker

- Medical history of hypotension, bradycardia, syncope or other significant
cardiovascular disease

- Medical history of difficulty breathing, asthma or chronic obstructive pulmonary
disease or other pulmonary disease

- Medical history of glaucoma, ocular hypertension or hypotony, punctual stenosis,
current use of other ophthalmic medications

- Previous adverse reaction to timolol or other beta-blockers

- Inability to self-administer eye drop due to physical or cognitive disorders

- Currently pregnant or breastfeeding

- Pregnant in the past year

- Non-english speaker
We found this trial at
1
site
2301 Holmes
Kansas City, Missouri 64108
816-404-1000
Truman Medical Center Located in the heart of downtown Kansas City, TMC Hospital Hill is...
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mi
from
Kansas City, MO
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