TREAT-BE Study (Treatment With Resection and Endoscopic Ablation Techniques for Barrett's Esophagus)

Patients will be enrolled in this study at the participating centers when evaluated in
gastro-intestinal (GI) clinics and endoscopy suites. Initial evaluation of patients will
include collection of data on demographics, assessment of risk factors such as smoking,
metabolic syndrome, family history and detailed medication history, and past surgical
history. All patients will be complete questionnaires regarding Gastroesophageal Reflux
Disease (GERD) symptoms, GERD related quality of life (QOL) and overall health related QOL.
Details of all previous endoscopic and surgical evaluation along with histopathology data
will be documented. Patients undergoing endoscopic evaluation at the participating centers
will have their endoscopic and histopathology results documented. This will include data
collection regarding use of advanced imaging techniques, details regarding tissue
acquisition, EET and adverse events. Patients undergoing esophagectomy will have surgical
details documented along with complications related to surgery. Similarly, details regarding
chemoradiation treatments will be documented .

Inclusion Criteria:

- Patients with Barrett's related neoplasia and dysplasia. Patients with esophageal
cancer

Exclusion Criteria:

- Patients with squamous cell carcinoma