Alcohol Versus Chlorhexidine With and Without Water
| Status: | Not yet recruiting |
|---|---|
| Conditions: | Infectious Disease |
| Therapuetic Areas: | Immunology / Infectious Diseases |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 6/25/2016 |
| Start Date: | December 2016 |
| End Date: | January 2018 |
| Contact: | Alexander Crespo |
| Email: | amc719@nyumc.org |
Efficacy of the Use of Alcohol-bases Solutions Versus Chlorhexidine With or Without Water for Hand Sanitation Prior to Surgical Procedure
Currently at NYU institutions, providine-iodine and chlorhexidine medicated soaps are
available as hand disinfection options. The purpose of this study is to determine the
relative efficacy of traditional hand scrubs with chlorhexidine with or without rinsing with
water after scrubbing is complete versus dry hand rubs with alcohol.
available as hand disinfection options. The purpose of this study is to determine the
relative efficacy of traditional hand scrubs with chlorhexidine with or without rinsing with
water after scrubbing is complete versus dry hand rubs with alcohol.
No current recommendations exist advocating the use of Providine-iodine or Chlorhexidine.
Providine-iodine is safe and effective at reducing skin colonization with gram positive and
negative bacteria, mycobacterium tuberculosis, fungi and viruses. Chlorhexidine similarly
disrupts cellular membranes. It is bacteriocidal and bacteriostatic and has immediate and
more lasting effect than iodine because it can bind to the stratum corneum of the skin and
is effective against gram positive and negative organisms, lipophilic viruses and yeasts.
All subjects who are employees of the NYU Hospital for Joint Diseases and have experience
with surgical hand disinfection will be asked to enroll. Subjects will be randomized into
one of three study arms using an online randomizer: (1) the standard chlorhexidine with
water rinse, (2) chlorhexidine without water rinse(experimental), and (3) standard
chlorhexidine followed by sterillium hand rub. After hand disinfection protocol has been
completed, each subject will have each hand cultured three times using a cotton swab culture
stick and sent to the microbiology lab for processing
Providine-iodine is safe and effective at reducing skin colonization with gram positive and
negative bacteria, mycobacterium tuberculosis, fungi and viruses. Chlorhexidine similarly
disrupts cellular membranes. It is bacteriocidal and bacteriostatic and has immediate and
more lasting effect than iodine because it can bind to the stratum corneum of the skin and
is effective against gram positive and negative organisms, lipophilic viruses and yeasts.
All subjects who are employees of the NYU Hospital for Joint Diseases and have experience
with surgical hand disinfection will be asked to enroll. Subjects will be randomized into
one of three study arms using an online randomizer: (1) the standard chlorhexidine with
water rinse, (2) chlorhexidine without water rinse(experimental), and (3) standard
chlorhexidine followed by sterillium hand rub. After hand disinfection protocol has been
completed, each subject will have each hand cultured three times using a cotton swab culture
stick and sent to the microbiology lab for processing
Inclusion Criteria:
- Orthopedic resident or surgical employee of NY U
- Over 21 years of age
- Procedural knowledge of correct aseptic scrub technique
Exclusion Criteria:
- No surgical experience
- Under 21 years of age
- Refusal to consent
We found this trial at
1
site
New York, New York 10016
Principal Investigator: Frank Liporace, MD
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