Optimizing Postoperative Cognition the Elderly
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Cognitive Studies, Hospital |
| Therapuetic Areas: | Psychiatry / Psychology, Other |
| Healthy: | No |
| Age Range: | 65 - Any |
| Updated: | 3/29/2019 |
| Start Date: | October 2015 |
| End Date: | August 2020 |
This study will recruit surgical patients more than 65 years old. Patients who participate
will wear a sticker on their forehead during surgery which monitors their brain waves
(electroencephalogram, EEG) and participate in memory testing before and after surgery. Brain
wave patterns will be compared between patients who have problems with memory and thinking
after surgery and those who do not. The hypothesis is that there will be characteristic brain
wave patients for who will go on to have problems with memory and thinking after surgery.
will wear a sticker on their forehead during surgery which monitors their brain waves
(electroencephalogram, EEG) and participate in memory testing before and after surgery. Brain
wave patterns will be compared between patients who have problems with memory and thinking
after surgery and those who do not. The hypothesis is that there will be characteristic brain
wave patients for who will go on to have problems with memory and thinking after surgery.
Eligible patients will be identified through the computerized scheduling system at the Icahn
School of Medicine at Mount Sinai. After informed consent, patients will complete cognitive
and tests at least one but not more than 30 days prior to surgery. In the recovery room the
Post Anesthesia Recovery Scale (PQRS), and CAM-ICU delirium screening will be administered.
Immediate recovery will be recorded using the Postoperative Recovery Scale (PQRS) on
postoperative day 1 and 3, and 1 week.
Longterm functional recovery will be measured with the Alzheimer's Disease Research Center
(ADRC) Instrumental Activities for Daily Living (IADL-24). Postsurgical complications will be
recorded including unplanned ICU admissions, postoperative myocardial infarction and stroke
(risk less than 1 % in most cases), wound infection and reoperation. The full cognitive and
functional battery will be repeated at 3 months and 1 year after surgery.
School of Medicine at Mount Sinai. After informed consent, patients will complete cognitive
and tests at least one but not more than 30 days prior to surgery. In the recovery room the
Post Anesthesia Recovery Scale (PQRS), and CAM-ICU delirium screening will be administered.
Immediate recovery will be recorded using the Postoperative Recovery Scale (PQRS) on
postoperative day 1 and 3, and 1 week.
Longterm functional recovery will be measured with the Alzheimer's Disease Research Center
(ADRC) Instrumental Activities for Daily Living (IADL-24). Postsurgical complications will be
recorded including unplanned ICU admissions, postoperative myocardial infarction and stroke
(risk less than 1 % in most cases), wound infection and reoperation. The full cognitive and
functional battery will be repeated at 3 months and 1 year after surgery.
Inclusion Criteria:
- 65 years of age and older
- having major elective non-cardiac surgery requiring general anesthesia requiring at
least a 2 day hospital stay
Exclusion Criteria:
- previous diagnosis of dementia, stroke, cardiac or intracranial surgery
- inability to consent or communicate in English or Spanish
- major uncorrected hearing or vision deficit, Parkinson's disease, or major psychiatric
disease which will be determined by phone interview and computer medical records
abstracted by the primary investigator.
We found this trial at
1
site
1428 Madison Ave
New York, New York 10029
New York, New York 10029
(212) 241-6500
Principal Investigator: Stacie Deiner, MD, MS
Icahn School of Medicine at Mount Sinai Icahn School of Medicine at Mount Sinai is...
Click here to add this to my saved trials
