Multidrug Resistant Gram-negative Bacilli Colonization and Infection in Burn

This is a prospective observational study. Patients will be followed during a single
admission for development of colonization or infection with MDR-GNB. Patient clinical
characteristics, including infections, surgeries, and antibiotic exposure, will be collected
in real-time.

Weekly surveillance wound and peri-rectal swabs and, if intubated, biweekly deep endotracheal
or tracheostomy aspirates will be collected, de-identified, and stored from all patients and
examined for the presence of MDR-GNB. All GNB isolates from blood, urine, respiratory, and
wound cultures will be collected, coded, and stored.

Inclusion Criteria:

1. Severe burn injury, including partial or full thickness burn 20% or more total body
surface area; or

2. inhalation injury; or

3. 18 years of age or older;

Exclusion Criteria:

1. Intensive care unit stay of less than 5 days;

2. ICU admission more than 48 hours after burn trauma.