A Study of Nivolumab in Advanced Non-Small Cell Lung Cancer (NSCLC)
Status: | Active, not recruiting |
---|---|
Conditions: | Lung Cancer, Cancer |
Therapuetic Areas: | Oncology |
Healthy: | No |
Age Range: | 18 - Any |
Updated: | 5/4/2018 |
Start Date: | November 13, 2015 |
End Date: | April 15, 2019 |
A Master Protocol of Phase 1/2 Studies of Nivolumab in Advanced NSCLC Using Nivolumab as Maintenance After Induction Chemotherapy or as First-line Treatment Alone or in Combination With Standard of Care Therapies (CheckMate 370: CHECKpoint Pathway and nivoluMAb Clinical Trial Evaluation 370)
The purpose of this study is to determine whether nivolumab monotherapy or in combination
with Standard of care (SOC) therapies will provide clinical benefit (i.e., PFS, OS, and DOR)
without unacceptable toxicity in advanced Non-Small Cell Lung Cancer patients.
with Standard of care (SOC) therapies will provide clinical benefit (i.e., PFS, OS, and DOR)
without unacceptable toxicity in advanced Non-Small Cell Lung Cancer patients.
Epidermal Growth Factor Receptor (EGFR), Anaplastic Lymphoma Kinase (ALK)
**Please note that the study is no longer enrolling patients for Groups A, B, C, and E.
**Please note that the study is no longer enrolling patients for Groups A, B, C, and E.
For more information regarding BMS clinical trial participation, please visit
www.BMSStudyConnect.com
Inclusion Criteria:
- Histologically confirmed locally advanced or stage IV NSCLC
- Eastern Cooperative Oncology Group (ECOG) Performance status (PS) 0-2
- Tumor tissue sections must be available for biomarker evaluation
Exclusion Criteria:
- Untreated or active/progressing Central Nervous system (CNS) metastases
- Active, known or suspected autoimmune disease
- Known history of testing positive for HIV or AIDS
- Active or chronic infection of hepatitis B virus or hepatitis C
We found this trial at
134
sites
9280 W. Sunset Road
Suite 100
Las Vegas, Nevada 89148
Las Vegas, Nevada 89148
702.952.1251

Comprehensive Cancer Centers of Nevada Comprehensive Cancer Centers of Nevada (CCCN) is the award-winning multidisciplinary...
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Brooke Army Medical Center Brooke Army Medical Center (BAMC) is the Flagship of Army Medicine!...
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1871 SE Tiffany Ave # 100
Port Saint Lucie, Florida 34952
Port Saint Lucie, Florida 34952
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Lehigh Valley Hospital At Lehigh Valley Health Network, we continually go the extra mile to...
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University of Maryland As a globally-connected university offering a world-class education, the University of Maryland...
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Sinai Hospital of Baltimore Sinai Hospital of Baltimore provides a broad array of high-quality, cost-effective...
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6410 Rockledge Dr #660
Bethesda, Maryland 20817
Bethesda, Maryland 20817
(301) 571-0019

Phone: 301-571-2016
Center for Cancer & Blood Disorders Widely recognized for its compassionate, expert care, the Center...
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Blacksburg, Virginia 24060
Phone: 540-381-5291
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Oncology Hematology Care Our more than 60 physicians and advanced practice providers throughout neighborhood offices...
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MetroHealth Med Ctr The MetroHealth System is one of the largest, most comprehensive health care...
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1717 13th St
Everett, Washington 98201
Everett, Washington 98201
(425) 297-5500

Phone: 425-297-5500
Providence Regional Cancer Partnership Founded in 2007, the Providence Regional Cancer Partnership is the result...
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8503 Arlington Blvd., Ste. 400
Fairfax, Virginia 22031
Fairfax, Virginia 22031
(703) 280-5390

Phone: 703-208-3173
Virginia Cancer Specialists, PC Now the world's most advanced cancer treatment capabilities can be found...
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501 N. Elam Avenue
Greensboro, North Carolina 27403
Greensboro, North Carolina 27403
336-832-1100

Phone: 336-832-0836
Cone Health Cancer Center Located adjacent to Wesley Long Hospital, our Cone Health Cancer Center...
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Cone Health Cancer Center Located adjacent to Wesley Long Hospital, our Cone Health Cancer Center...
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Tennessee Oncology, PLLC Since 1976 Tennessee Oncology has been providing quality cancer care. In 2013,...
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5900 Lake Wright Dr
Norfolk, Virginia 23502
Norfolk, Virginia 23502
(757) 466-8683

Phone: 757-466-8683
Virginia Oncology Associates Virginia Oncology Associates is an oncology and hematology practice of physicians, specializing...
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