Safety, Pharmacokinetics and Pharmacodynamics of BMS-936559 in Severe Sepsis
| Status: | Terminated |
|---|---|
| Conditions: | Hospital |
| Therapuetic Areas: | Other |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 9/16/2017 |
| Start Date: | December 2, 2015 |
| End Date: | March 15, 2017 |
A Phase 1b/2a, Randomized, Double-Blinded, Placebo-Controlled, Multicenter Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BMS-936559 in Subjects With Severe Sepsis
The purpose of this study is to determine whether BMS-936559 is safe and has the desired
pharmacologic activity in patients who have severe sepsis.
pharmacologic activity in patients who have severe sepsis.
For more information regarding BMS clinical trial participation, please visit
www.BMSStudyConnect.com
Inclusion Criteria:
- Severe sepsis or septic shock for at least 24 hours
- Documented or suspected infection
- Sepsis-induced immunosuppression
- Men and women ≥ 18 years old
Exclusion Criteria:
- Autoimmune disease
- Organ transplant or bone marrow transplant
- Cancer treated in the past 6 months
- Hepatitis B virus (HBV) Infection
- Human Immunodeficiency Virus (HIV) infection and not on therapy prior to this episode
of sepsis
- Hepatitis C virus (HCV) infection and still has virus (not cured)
We found this trial at
14
sites
660 S Euclid Ave
Saint Louis, Missouri 63110
Saint Louis, Missouri 63110
(314) 362-5000
Washington University School of Medicine Washington University Physicians is the clinical practice of the School...
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Emory University Emory University, recognized internationally for its outstanding liberal artscolleges, graduate and professional schools,...
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Emory University Emory University, recognized internationally for its outstanding liberal artscolleges, graduate and professional schools,...
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University of Florida The University of Florida (UF) is a major, public, comprehensive, land-grant, research...
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Ohio State University The Ohio State University’s main Columbus campus is one of America’s largest...
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Baystate Medical Center Baystate Medical Center (BMC), in Springfield, Massachusetts, is an academic, research, and...
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