A Trial Comparing Cardiovascular Safety of Degarelix Versus Leuprolide in Patients With Advanced Prostate Cancer and Cardiovascular Disease



Status:Recruiting
Conditions:Prostate Cancer, Cancer, Peripheral Vascular Disease
Therapuetic Areas:Cardiology / Vascular Diseases, Oncology
Healthy:No
Age Range:Any
Updated:3/30/2019
Start Date:April 2016
End Date:July 2021
Contact:Global Clinical Compliance
Email:DK0-Disclosure@ferring.com

Use our guide to learn which trials are right for you!

Trial Summary
Trial Overview
Inclusion Criteria

A Multi-Center, Randomized, Assessor-Blind, Controlled Trial Comparing the Occurrence of Major Adverse Cardiovascular Events (MACEs) in Patients With Prostate Cancer and Cardiovascular Disease Receiving Degarelix (Gonadotropin-Releasing Hormone (GnRH) Receptor Antagonist) or Leuprolide (GnRH Receptor Agonist)

The purpose of this trial is to test if a marketed drug for advanced prostate cancer
(FIRMAGON) can reduce the risk of cardiovascular complications as compared to another
marketed drug for advanced prostate cancer (LUPRON DEPOT) in patients with prostate cancer
and cardiovascular disease.


Inclusion Criteria:

- Advanced prostate cancer

- Indication to initiate androgen deprivation therapy (ADT)

- Predefined cardiovascular disease

Exclusion Criteria:

- Previous or current hormonal management of prostate cancer (unless terminated at least
12 months prior to trial)

- Acute cardiovascular disease in the previous 30 days
We found this trial at
61
sites
Michigan Institute of Urology, P.C.
Troy, Michigan 48084
?
mi
from
Troy, MI
Click here to add this to my saved trials
San Diego Clinical Trials
6719 Alvarado Road
San Diego, California 92120
619-287-6000
?
mi
from
San Diego, CA
Click here to add this to my saved trials
Albany Medical College
47 New Scotland Ave
Albany, New York 12208
(518) 262-3125
Albany Medical College Albany Medical Center is northeastern New York's only academic health sciences center...
?
mi
from
Albany, NY
Click here to add this to my saved trials
Urology Group of New Mexico
Albuquerque, New Mexico 87109
?
mi
from
Albuquerque, NM
Click here to add this to my saved trials
Pacific Cancer Medical Center
Anaheim, California 92801
?
mi
from
Anaheim, CA
Click here to add this to my saved trials
Alaska Clinical Research Center, LLC
Anchorage, Alaska 99508
?
mi
from
Anchorage, AK
Click here to add this to my saved trials
Urologic Consultants of Southeaster PA LLP
1 Presidential Boulevard
Bala-Cynwyd, Pennsylvania 19004
?
mi
from
Bala-Cynwyd, PA
Click here to add this to my saved trials
Urology Center of Alabama PC
Birmingham, Alabama 35209
?
mi
from
Birmingham, AL
Click here to add this to my saved trials
Montefiore Medical Center PRIME
Bronx, New York 10467
?
mi
from
Bronx, NY
Click here to add this to my saved trials
Seattle Urology Research Center
Burien, Washington 98166
?
mi
from
Burien, WA
Click here to add this to my saved trials
Medical University of South Carolina
Charleston, South Carolina 29425
?
mi
from
Charleston, SC
Click here to add this to my saved trials
Erlanger Health System
Chattanooga, Tennessee 37403
?
mi
from
Chattanooga, TN
Click here to add this to my saved trials
The Carl and Edyth Lindner Center for Research and Education at the Christ Hospital
Cincinnati, Ohio 45219
?
mi
from
Cincinnati, OH
Click here to add this to my saved trials
Carolina Clinical Trials
Concord, North Carolina 28025
?
mi
from
Concord, NC
Click here to add this to my saved trials
Urology Clinics of North Texas
Dallas, Texas 75231
?
mi
from
Dallas, TX
Click here to add this to my saved trials
Signal Point Clinical Research Center
Dayton, Ohio 45409
?
mi
from
Dayton, OH
Click here to add this to my saved trials
Urology Center of Colorado
Denver, Colorado 80211
?
mi
from
Denver, CO
Click here to add this to my saved trials
Urology of Indiana
Greenwood, Indiana 46143
?
mi
from
Greenwood, IN
Click here to add this to my saved trials
First Urology PSC
Jeffersonville, Indiana 47130
?
mi
from
Jeffersonville, IN
Click here to add this to my saved trials
University of Kansas Medical Center Research Institute, Inc.
Kansas City, Kansas
?
mi
from
Kansas City, KS
Click here to add this to my saved trials
Kansas City VA Medical Center
Kansas City, Missouri 64128
?
mi
from
Kansas City, MO
Click here to add this to my saved trials
Okanagan Health Surgical Centre
Kelowna, British Columbia
?
mi
from
Kelowna,
Click here to add this to my saved trials
Comprehensive Urologic Care
Lake Barrington, Illinois
?
mi
from
Lake Barrington, IL
Click here to add this to my saved trials
Lancaster Urology
Lancaster, Pennsylvania 17604
?
mi
from
Lancaster, PA
Click here to add this to my saved trials
Premier Urology Associates
Lawrenceville, New Jersey
?
mi
from
Lawrenceville, NJ
Click here to add this to my saved trials
Kansas City Urology Care
Lenexa, Kansas 66214
?
mi
from
Lenexa, KS
Click here to add this to my saved trials
Clinical Trials Research
Lincoln, California 95648
?
mi
from
Lincoln, CA
Click here to add this to my saved trials
Urology Associates, PA
Little Rock, Arkansas 72211
?
mi
from
Little Rock, AR
Click here to add this to my saved trials
Tower Urology Medical Group
Los Angeles, California
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
San Marcus Research Clinic
Miami, Florida 33015
?
mi
from
Miami, FL
Click here to add this to my saved trials
Mount Sinai Comprehensive Cancer Center
Miami Beach, Florida 33140
?
mi
from
Miami Beach, FL
Click here to add this to my saved trials
Clinical Research Solutions, LLC
Middleburg Heights, Ohio 44130
?
mi
from
Middleburg Heights, OH
Click here to add this to my saved trials
Medical College of Wisconsin
8701 W Watertown Plank Rd
Milwaukee, Wisconsin
(414) 955-8296
Medical College of Wisconsin The Medical College (MCW) of Wisconsin is a major national research...
?
mi
from
Milwaukee, WI
Click here to add this to my saved trials
Delaware Valley Urology LLC Westhampton
Mount Laurel, New Jersey
?
mi
from
Mount Laurel, NJ
Click here to add this to my saved trials
Tulane University Health Sciences Center
1430 Tulane Ave Suite SL32
New Orleans, Louisiana 70112
(504) 588-5912
Tulane University Health Sciences Center One of the nation's most recognized centers for medical education,...
?
mi
from
New Orleans, LA
Click here to add this to my saved trials
Manhattan Medical Research Practice PLLC
New York, New York 10016
?
mi
from
New York, NY
Click here to add this to my saved trials
Memorial Sloan Kettering Cancer Center
1275 York Ave
New York, New York 10021
(212) 639-2000
Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center — the world's oldest and...
?
mi
from
New York, NY
Click here to add this to my saved trials
Premier Medical Group of the Hudson Valley PC
Newburgh, New York 12550
?
mi
from
Newburgh, NY
Click here to add this to my saved trials
Urology of Virginia
Norfolk, Virginia 23502
?
mi
from
Norfolk, VA
Click here to add this to my saved trials
University of Oklahoma Peggy and Charles Stephenson Cancer Center
Oklahoma City, Oklahoma 73104
?
mi
from
Oklahoma City, OK
Click here to add this to my saved trials
University of California, Irvine Medical Center
101 The City Drive South
Orange, California 92868
714-456-7890
University of California, Irvine Medical Center We are UC Irvine Health. We are a devoted...
?
mi
from
Orange, CA
Click here to add this to my saved trials
Clinical Research Center of Florida
Pompano Beach, Florida 33060
?
mi
from
Pompano Beach, FL
Click here to add this to my saved trials
Premier Medical Group
Poughkeepsie, New York 12601
?
mi
from
Poughkeepsie, NY
Click here to add this to my saved trials
Virginia Urology Center
Richmond, Virginia 23235
?
mi
from
Richmond, VA
Click here to add this to my saved trials
Veterans Affairs Medical Center-Salisbury, NC
Salisbury, North Carolina 28144
?
mi
from
Salisbury, NC
Click here to add this to my saved trials
Urology Associates of the Central Coast
San Luis Obispo, California 93401
?
mi
from
San Luis Obispo, CA
Click here to add this to my saved trials
University of Washington School of Medicine
Seattle, Washington 98195
?
mi
from
Seattle, WA
Click here to add this to my saved trials
Regional Urology
Shreveport, Louisiana 71106
?
mi
from
Shreveport, LA
Click here to add this to my saved trials
Springfield Clinic, LLP
Springfield, Illinois 62703
?
mi
from
Springfield, IL
Click here to add this to my saved trials
Oregon Urology Institute
Springfield, Oregon 97477
?
mi
from
Springfield, OR
Click here to add this to my saved trials
Madigan Army Medical Center
9040 Jackson Ave
Tacoma, Washington 98431
(253) 968-1110
Madigan Army Medical Center Located on Joint Base Lewis-McChord, Madigan Army Medical Center comprises a...
?
mi
from
Tacoma, WA
Click here to add this to my saved trials
Florida Urology Partners
Tampa, Florida 33607
?
mi
from
Tampa, FL
Click here to add this to my saved trials
Skyline Urology
Torrance, California 90505
?
mi
from
Torrance, CA
Click here to add this to my saved trials
Chesapeake Urology Associates
7505 Osler Drive
Towson, Maryland 21204
?
mi
from
Towson, MD
Click here to add this to my saved trials
Urological Associates of Southern Arizona, PC
Tucson, Arizona 85715
?
mi
from
Tucson, AZ
Click here to add this to my saved trials
Arizona Institute of Urology
Tucson, Arizona 85715
?
mi
from
Tucson, AZ
Click here to add this to my saved trials
Urologic Surgeons of Washington
Washington, District of Columbia 20036
?
mi
from
Washington,
Click here to add this to my saved trials
G. Patsias, M.D., PA
Wellington, Florida 33449
?
mi
from
Wellington, FL
Click here to add this to my saved trials
The Iowa Clinic
West Des Moines, Iowa 50266
?
mi
from
West Des Moines, IA
Click here to add this to my saved trials
Innovative Clinical Research Institute, LLC
Whittier, California 90603
?
mi
from
Whittier, CA
Click here to add this to my saved trials
PMG Research of Winston-Salem
1901 S Hawthorne Rd #306
Winston-Salem, North Carolina 27103
(336) 768-8062
PMG Research of Winston-Salem PMG Research of Winston-Salem, founded in 1979, occupies a 10,000 square...
?
mi
from
Winston-Salem, NC
Click here to add this to my saved trials