Evaluating the Effect of Perioperative Caloric Restriction Program on Perioperative Outcomes in Patients With Obesity and Endometrial Cancer
| Status: | Recruiting |
|---|---|
| Conditions: | Cervical Cancer, Cancer, Endometrial Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 10/10/2018 |
| Start Date: | July 2015 |
| Contact: | Emily Ko, MD |
| Email: | PennCancerTrials@emergingmed.com |
| Phone: | 855-216-0098 |
80% of endometrial cancer patients are overweight or obese. Preclinical and clinical data
have shown that caloric restriction (CR) protects against organ injury and decreases
perioperative morbidity. This is a feasibility trial to evaluate the effect of a 6 week
perioperative CR on surgical and patient-reported outcomes in 20 obese newly diagnosed
endometrial cancer patients. The intervention will provide individualized CR program, meal
replacement products and nutritional counselling sessions.
have shown that caloric restriction (CR) protects against organ injury and decreases
perioperative morbidity. This is a feasibility trial to evaluate the effect of a 6 week
perioperative CR on surgical and patient-reported outcomes in 20 obese newly diagnosed
endometrial cancer patients. The intervention will provide individualized CR program, meal
replacement products and nutritional counselling sessions.
Inclusion Criteria:
- Newly diagnosed with Endometrial Cancer
- BMI30 kg/m2
- 18 year of age or older
- Scheduled for definitive surgical intervention (hysterectomy, bilateral
salpingoopherectomy with or without lymphadenectomy) in the following 2-3 weeks as
part of the standard of care
- Have ECOG performance status of 0-1
- Have a life expectancy of at least 1 year
Exclusion Criteria:
- Inability to communicate in English
- BMI30 kg/m2
- Age18
- Have any uncontrolled serious medical or psychiatric conditions that would affect
their ability to participate in an intervention study, (e.g., severe/uncontrolled
diabetes mellitus, severe cardiac and/or pulmonary disease and/or depression)
- Diagnosed with any other invasive malignancy currently, in the last five years or
expected to undergo active treatment with either cytotoxic chemotherapy or radiation
during the 6 week caloric restriction period
We found this trial at
1
site
3400 Civic Center Blvd
Philadelphia, Pennsylvania 19104
Philadelphia, Pennsylvania 19104
(215) 662-6065
Principal Investigator: Emily Ko, MD
Phone: 855-216-0098
Abramson Cancer Center of the University of Pennsylvania The Abramson Cancer Center of the University...
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