Illness Management and Parental Adjustment to Cancer Treatment

The proposed trial will test the efficacy of the parent-focused clinic-based Parent
Uncertainty Management Intervention (PUMI) to improve the outcomes of children newly
diagnosed with cancer and their parents. Participants will be randomly assigned to receive
equivalent doses of either the PUMI or an Education/Support (ESO) group. Theoretically driven
by Mishel's model of illness uncertainty, the PUMI will teach parents about uncertainty
prevention and management through the use of medically-specific communication, information
management, and problem-solving skills via in-clinic sessions and an online portal. Parents
and children will complete measures online at baseline, 1-week, and 3-, 6-, and 12-month
follow-ups.

Inclusion Criteria:

- The child has been diagnosed with leukemia or lymphoma, malignant solid tumor, or
malignant brain tumor

- The child is being treated for cancer and returning to the medical center (CCHMC or
OUHSC).

- The child is 18 years of age or younger

- Recruitment occurs within 2-12 weeks post diagnosis

- The parent is responsible for care and is willing to give consent and participate

- The child is willing to give assent or consent and participate (only for children 8
years old and older)

- The parent gives patient permission to participate.

- Parent is fluent in English

Exclusion Criteria:

- The child is experiencing an imminent medical crisis necessitating significant medical
intervention

- The child with cancer is determined to be in the terminal phase of illness and/or is
receiving end of life care

- The diagnosis is determined to be a relapse or a second malignancy

- The parent is currently being treated for a serious psychiatric disorder, or,
evidences mental retardation

- The parent is younger than 18 years of age

- The parent is not English speaking

- The parent is unwilling to give written permission for child participation

- If the patient's treatment visit schedule is too infrequent to meet the study visit
timeline requirements