Lowering Caloric Density of the Diet



Status:Active, not recruiting
Conditions:Obesity Weight Loss
Therapuetic Areas:Endocrinology
Healthy:No
Age Range:18 - 65
Updated:4/17/2018
Start Date:December 2015
End Date:January 2020

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For weight loss to occur, energy intake needs to be reduced to incur an energy deficit. One
dietary strategy that may facilitate reducing energy intake and enhancing weight loss is
consuming a diet low in dietary energy density (ED). The ED of a given food, defined as the
ratio of energy of the food to the weight of the food (kcal/g), is largely determined by
water content, but is also affected by fat and fiber. Although the 2010 Dietary Guidelines
encourage an eating pattern low in energy density (ED) to manage weight, it is currently not
known what the best strategy is for reducing ED in the diet. Eating a greater number of foods
low in ED or reducing the number of foods high in ED may reduce overall dietary ED. As ED is
believed to reduce intake by allowing a greater weight of food relative to total energy
consumed assisting with enhancing feelings of fullness, it is anticipated that either
increasing consumption of low-ED foods in the diet alone or combining an increase in
consumption of low-ED foods with a decrease in consumption of high-ED foods may be the best
strategies for reducing overall dietary ED for weight loss.


Inclusion Criteria:

- 1) age between 18 and 65 years and 2) a body mass index (BMI)7 between 27 and 45
kg/m2.

Exclusion Criteria:

1. report a heart condition, chest pain during periods of activity or rest, or loss of
consciousness on the Physical Activity Readiness Questionnaire (PAR-Q)8 (medical
conditions that could limit exercise for safety reasons will be required to obtain
written physician consent before participating in the investigation)

2. report being unable to walk for 2 blocks (1/4 mile) without stopping

3. are currently participating in a weight loss program and/or taking weight loss
medication or lost > 5% of body weight during the past 6 months

4. report major psychiatric diseases or organic brain syndromes

5. have had bariatric surgery or are planning to have bariatric surgery within the next 4
months

6. intend to move outside of the metropolitan area within the time frame of the
investigation

7. are pregnant, lactating, < 6 months post-partum, or plan to become pregnant during the
investigation.
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Knoxville, Tennessee 37920
Phone: 865-974-0752
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