Nanodiamond Modified Gutta Percha (NDGP) Composite for Non-surgical Root Canal Therapy (RCT) Filler Material
| Status: | Recruiting |
|---|---|
| Conditions: | Dental |
| Therapuetic Areas: | Dental / Maxillofacial Surgery |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/28/2018 |
| Start Date: | March 2016 |
| End Date: | May 2020 |
| Contact: | Mo K Kang, Ph.D.,D.D.S. |
| Email: | mkang@dentistry.ucla.edu |
| Phone: | (310) 825-8048 |
Nanodiamond Modified Gutta Percha (NDGP) Composite for Non-surgical Root Canal Therapy (RCT) Filler Material Applied by Vertical Condensation Obturation Procedure
Non-surgical root canal therapy (RCT) represents a standard of treatment that addresses
infected pulp tissue in teeth and protects against future infection while preserving the
tooth for the patient for mainly cosmetic purposes. RCT is offered as the better cosmetic,
cheaper, and less time intensive treatment option for a patient compared to those of dental
implantation. Dental implantation is the alternative to RCT, and they are both originally
offered at the time of the initial consultation. RCT involves non-surgically removing dental
pulp comprising blood vessels and nerve tissue, decontaminating residually infected tissue,
and using a filler material to replace the non-surgically created space where the pulp was
removed. Currently, standard of care treatment for RCT utilizes gutta-percha as the root
canal filling material. Our research group has previously demonstrated NDGP's improvement in
tensile strength compared to those of gutta-percha. This research studies a new type of
filler, gutta-percha modified by the addition of nanodiamond material (NDGP). This is an
equivalence study of NDGP and standard gutta-percha administration.
infected pulp tissue in teeth and protects against future infection while preserving the
tooth for the patient for mainly cosmetic purposes. RCT is offered as the better cosmetic,
cheaper, and less time intensive treatment option for a patient compared to those of dental
implantation. Dental implantation is the alternative to RCT, and they are both originally
offered at the time of the initial consultation. RCT involves non-surgically removing dental
pulp comprising blood vessels and nerve tissue, decontaminating residually infected tissue,
and using a filler material to replace the non-surgically created space where the pulp was
removed. Currently, standard of care treatment for RCT utilizes gutta-percha as the root
canal filling material. Our research group has previously demonstrated NDGP's improvement in
tensile strength compared to those of gutta-percha. This research studies a new type of
filler, gutta-percha modified by the addition of nanodiamond material (NDGP). This is an
equivalence study of NDGP and standard gutta-percha administration.
Inclusion Criteria:
- 18 years old or older when patient is referred to UCLA endodontics department for root
canal therapy
- Patient referral to UCLA endodontics department for root canal therapy
Exclusion Criteria:
- preoperative periodontal disease
- prior non-surgical and surgical endodontic treatment
- currently taking medications used to treat osteoporosis or any form of IV
biphosphonates
- allergic to dental materials
- dental phobia
- MD consult/medically compromised/prophylaxis needed
- developmental/congenital disorders
- craniofacial disorder/syndromic cases
- low pain tolerance ascertained from past dental experience
- current moderate to severe periodontitis
- previous RCT/initiated pulp therapy
- previous apical surgery
- previous surgical root canal procedure
- with psychiatric and/or mental health history
- poor oral hygiene
- poor diet
- illicit and/or recreational drug use
- complicated dental history
We found this trial at
1
site
Los Angeles, California 90095
310-825-4321
Principal Investigator: Dean Ho, M.S., Ph.D.
Phone: 310-825-8048
University of California at Los Angeles The University of California, Los Angeles (UCLA) is an...
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