Phase 2 Study of NGM282 in Patients With Primary Sclerosing Cholangitis



Status:Completed
Conditions:Gastrointestinal, Gastrointestinal
Therapuetic Areas:Gastroenterology
Healthy:No
Age Range:18 - 75
Updated:7/20/2018
Start Date:March 2016
End Date:June 2017

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Trial Summary
Trial Overview
Inclusion Criteria

A Phase 2, Randomized, Double Blind, Placebo Controlled, Parallel Group, Multiple Center Study to Evaluate the Safety, Tolerability, and Efficacy of NGM282 Administered for 12 Weeks in Patients With Primary Sclerosing Cholangitis

The purpose of this study is to determine the safety, tolerability, and activity of NGM282 in
patients with Primary Sclerosing Cholangitis.


Inclusion Criteria:

- Confirmed diagnosis of PSC

Exclusion Criteria:

- Clinically significant acute or chronic liver disease of an etiology other than PSC

- Secondary or IgG4 related sclerosing cholangitis
We found this trial at
25
sites
NGM Clinical Study Site 125
Southlake, Texas
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Southlake, TX
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NGM Clinical Study Site 106
Aurora, Colorado
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Aurora, CO
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NGM Clinical Study Site 904
Charlottesville, Virginia
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Charlottesville, VA
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NGM Clinical Study Site 120
Cincinnati, Ohio
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Cincinnati, OH
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NGM Clinical Study Site 910
Dallas, Texas
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Dallas, TX
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NGM Clinical Study Site 101
Detroit, Michigan
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Detroit, MI
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NGM Clinical Study Site 903
Durham, North Carolina
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Durham, NC
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NGM Clinical Study Site 110
Gainesville, Florida
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Gainesville, FL
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NGM Clinical Study Site 119
Houston, Texas
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Houston, TX
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NGM Clinical Study Site 109
Indianapolis, Indiana
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Indianapolis, IN
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NGM Clinical Study Site 102
Kansas City, Missouri
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Kansas City, MO
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NGM Clinical Study Site 124
Lakewood Ranch, Florida
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Lakewood Ranch, FL
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NGM Clinical Study Site 105
Miami, Florida
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Miami, FL
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NGM Clinical Study Site 114
Nashville, Tennessee
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Nashville, TN
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NGM Clinical Study Site 103
New York, New York
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New York, NY
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NGM Clinical Study Site 912
Newport News, Virginia
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Newport News, VA
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NGM Clinical Study Site 101
Norfolk, Virginia
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Norfolk, VA
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NGM Clinical Study Site 301
Paris,
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Paris,
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NGM Clinical Study Site 911
Richmond, Virginia
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Richmond, VA
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NGM Clinical Study Site 118
Sacramento, California
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Sacramento, CA
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NGM Clinical Study Site 107
Saint Louis, Missouri
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Saint Louis, MO
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NGM Clinical Study Site 112
San Clemente, California
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San Clemente, CA
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NGM Clinical Study Site 127
San Francisco, California
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San Francisco, CA
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NGM Clinical Study Site 908
Seattle, Washington
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Seattle, WA
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NGM Clinical Study Site 115
Washington, District of Columbia
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Washington,
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