Study of Nerve Repair and Reconstruction Associated With Major Extremity Trauma



Status:Recruiting
Healthy:No
Age Range:18 - 65
Updated:3/17/2019
Start Date:March 2016
End Date:September 2019
Contact:Elizabeth Wysocki, MS
Email:ewysock2@jhu.edu
Phone:410-955-0396

Use our guide to learn which trials are right for you!

A Multi Center Prospective Observational Study of Nerve Repair and Reconstruction Associated With Major Extremity Trauma

This is a multi-center prospective observational study that will capture detailed information
about the treatment and long term outcomes of 250 patients with PNI resulting from upper
extremity trauma. The study will focus on a young adult population to include individuals
ages 18-65. Patients with PNI will be recruited during the hospitalization for initial
treatment of the upper extremity injury. Additional patients may be identified during clinic
visits for on-going treatment of upper extremity injuries as nerve injuries evolve or upon
referral from outside physicians. However, all eligible nerve injuries must be treated within
6 months of the initial upper extremity trauma. Outcomes will be assessed at 3, 6, 12, 18 and
24 months following diagnosis of the nerve injury. All assessments will take place in the
clinic and will include a patient interview and a brief exam to evaluate sensory and motor
function.


Inclusion Criteria:

1. Ages 18-65

2. Sustained a peripheral nerve injury (including iatrogenic injuries and partial nerve
injuries) resulting from upper extremity trauma meeting the following criteria:

1. Involves injury or dysfunction to motor, or motor and sensory function of the
axillary, radial, median, ulnar, or musculocutaneous nerve with injury localized
distal to the brachial plexus cord level and proximal to the distal flexion
crease of the wrist

2. Involves a "mixed" nerve segment (i.e. involves a location of any of the above
specified nerves that can be expected to have both sensory and motor axons
present) but does not include sensory only distal terminations of the same
nerves.

3. Receiving surgical treatment (i.e. exploration, neurolysis, repair or reconstruction,
nerve or tendon transfer) within 6 months of the initial injury.

Exclusion Criteria:

1. Injuries to the brachial plexus roots, trunks, divisions and cords

2. Injuries to the nerves distal to the distal flexion crease of the wrist

3. Injuries that involve a distal extension of the parent nerve that is considered
sensory only (superficial radial nerve, lateral ante brachial cutaneous nerve, etc)

4. Previous motor or sensory deficit prior to injury (e.g. resulting from trauma, stroke,
muscular, neurologic, neuromuscular disorder, etc.)

5. Documented psychiatric disorder that limits ability to consent and maintain follow-up

6. Unable to speak either English or Spanish

7. Severe problems with maintaining follow up (e.g patients who are prisoners or homeless
at time of injury or who are intellectually challenged without adequate family
support).
We found this trial at
17
sites
Cleveland, Ohio 44109
?
mi
from
Cleveland, OH
Click here to add this to my saved trials
1000 Blythe Blvd
Charlotte, North Carolina 28203
(704) 355-2000
?
mi
from
Charlotte, NC
Click here to add this to my saved trials
1800 NW 10th Ave
Miami, Florida 33136
?
mi
from
Miami, FL
Click here to add this to my saved trials
Albuquerque, New Mexico 87131
?
mi
from
Albuquerque, NM
Click here to add this to my saved trials
22 S Greene St
Baltimore, Maryland 21201
(410) 328-8667
University of Maryland Medical Center Founded in 1823 as the Baltimore Infirmary, the University of...
?
mi
from
Baltimore, MD
Click here to add this to my saved trials
?
mi
from
Baltimore, MD
Click here to add this to my saved trials
8901 Rockville Pike
Bethesda, Maryland 20889
(301) 295-4000
Walter Reed National Military Medical Center The Walter Reed National Military Medical Center is one...
?
mi
from
Bethesda, MD
Click here to add this to my saved trials
Bloomington, Indiana
?
mi
from
Bloomington, IN
Click here to add this to my saved trials
Denver, Colorado 80204
?
mi
from
Denver, CO
Click here to add this to my saved trials
?
mi
from
Houston, TX
Click here to add this to my saved trials
Minneapolis, Minnesota 55414
?
mi
from
Minneapolis, MN
Click here to add this to my saved trials
Nashville, Tennessee 37212
?
mi
from
Nashville, TN
Click here to add this to my saved trials
Oklahoma City, Oklahoma
?
mi
from
Oklahoma City, OK
Click here to add this to my saved trials
800 Spruce St
Philadelphia, Pennsylvania 19107
215-829-3000
Pennsylvania Hospital Pennsylvania Hospital, the nation's first hospital, has been a leader in patient care,...
?
mi
from
Philadelphia, PA
Click here to add this to my saved trials
1250 E. Marshall St.
Richmond, Virginia 23298
(804) 828-9000
Virginia Commonwealth University Medical Center The Virginia Commonwealth University Health System is an urban, comprehensive...
?
mi
from
Richmond, VA
Click here to add this to my saved trials
?
mi
from
San Antonio, TX
Click here to add this to my saved trials
Winston-Salem, North Carolina 27157
?
mi
from
Winston-Salem, NC
Click here to add this to my saved trials