Safety and Efficacy Study of a Protease Activated Receptor-4 Antagonist Being Tested to Reduce the Chances of Having Additional Strokes or "Mini Strokes"
Status: | Completed |
---|---|
Conditions: | Cardiology |
Therapuetic Areas: | Cardiology / Vascular Diseases |
Healthy: | No |
Age Range: | 18 - Any |
Updated: | 12/16/2018 |
Start Date: | April 25, 2016 |
End Date: | March 31, 2017 |
A Phase 2, Placebo Controlled, Randomized, Double-Blind, Parallel-Arm Study to Evaluate Efficacy and Safety of BMS- 986141 For the Prevention of Recurrent Brain Infarction in Subjects Receiving Acetylsalicylic Acid (ASA) Following Acute Ischemic Stroke or Transient Ischemic Attack
The purpose of this study is to determine whether BMS-986141 is effective in reducing the
recurrence of stroke in people who recently had a stroke, or a transient ischemic attack
(known as a TIA or "mini stroke") and are receiving acetylsalicylic acid (also known as
aspirin or ASA) to treat the stroke or TIA.
recurrence of stroke in people who recently had a stroke, or a transient ischemic attack
(known as a TIA or "mini stroke") and are receiving acetylsalicylic acid (also known as
aspirin or ASA) to treat the stroke or TIA.
For more information regarding BMS clinical trial participation, please visit
www.BMSStudyConnect.com
Inclusion Criteria:
- Male or female, age 18 or older
- Must have had a very recent stroke or transient ischemic attack ("mini stroke") that
can be confirmed by the study doctor
- Able to be assigned to a study group no later than 48 hours after the stroke occurred
- Has an image of the brain that confirms that the stroke was not caused by hemorrhage
or other reason that could explain symptoms
Exclusion Criteria:
- A suspicion by the study doctor that the transient ischemic attack or stroke was
caused by a blood clot that formed in the heart; examples of this include history of
an abnormal heart rhythm known as atrial fibrillation or a ventricular aneurysm or
defect of the heart.
- Any condition requiring treatment with an anticoagulant
- History of intracranial hemorrhage ("bleeding in the brain")
- Gastrointestinal ("stomach or intestinal") bleeding in the last 3 months that required
treatment
- Planned or anticipated invasive surgery or procedure during the study
- Unable to tolerate MRI procedures.
We found this trial at
28
sites
Duke Univ Med Ctr As a world-class academic and health care system, Duke Medicine strives...
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Tufts Medical Center Tufts Medical Center is an internationally-respected academic medical center – a teaching...
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University of Florida The University of Florida (UF) is a major, public, comprehensive, land-grant, research...
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3400 Spruce St
Philadelphia, Pennsylvania 19104
Philadelphia, Pennsylvania 19104
(215) 662-4000
Hospital of the University of Pennsylvania The Hospital of the University of Pennsylvania (HUP) is...
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4805 Northeast Glisan Street
Portland, Oregon 97213
Portland, Oregon 97213
(503) 215-1111
Providence Portland Medical Center We strive to give those we serve exceptional, compassionate health care...
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3181 Southwest Sam Jackson Park Road
Portland, Oregon 97239
Portland, Oregon 97239
503 494-8311
Phone: 503-494-6865
Oregon Health and Science University In 1887, the inaugural class of the University of Oregon...
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171 Ashley Avenue
Charleston, South Carolina 29425
Charleston, South Carolina 29425
843-792-1414
Medical University of South Carolina The Medical University of South Carolina (MUSC) has grown from...
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University of Louisville The University of Louisville is a state supported research university located in...
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West Virginia University West Virginia University, founded in 1867, has a long and rich history...
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Florida Hospital Florida Hospital is one of the country
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Providence St. Vincent Medical Center Providence St. Vincent is renowned for its many centers of...
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