The SLIM Study: Sling and Botox® Injection for Mixed Urinary Incontinence
| Status: | Recruiting |
|---|---|
| Conditions: | Urology, Urology |
| Therapuetic Areas: | Nephrology / Urology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 1/20/2019 |
| Start Date: | February 2016 |
| End Date: | December 2019 |
| Contact: | Meera Tavathia, MPH |
| Email: | meera.tavathia@nm.org |
| Phone: | 312-926-7846 |
This double-blind randomized controlled trial seeks to find a better treatment for women with
mixed urinary incontinence (both stress and urgency incontinence). The primary aim is to
determine whether midurethral sling surgery combined with injections of onabotulinumtoxinA
(Botox®) into the detrusor muscle of the bladder improves symptoms of mixed urinary
incontinence better than sling surgery alone.
mixed urinary incontinence (both stress and urgency incontinence). The primary aim is to
determine whether midurethral sling surgery combined with injections of onabotulinumtoxinA
(Botox®) into the detrusor muscle of the bladder improves symptoms of mixed urinary
incontinence better than sling surgery alone.
Inclusion Criteria:
- Undergoing mid-urethral sling surgery
- Have symptoms of both stress and urgency urinary incontinence
- Able to consent, fill out study documents, and complete all study procedures and
follow-up visits
- At least 18 years of age
- English speaking
- Be able and willing to learn clean intermittent self catheterization technique
Exclusion Criteria:
- History of recurrent UTI (defined as three culture proven UTIs within last 12 months)
- Systemic neuromuscular disease known to affect the lower urinary tract
- Undergoing concomitant prolapse surgery
- Previous incontinence surgery
- Treatment with anticholinergic medication in the last 2 months
- Previous bladder injection with onabotulinumtoxinA
- Prisoner Status
- Pregnancy
We found this trial at
1
site
Chicago, Illinois 60611
Principal Investigator: Kimberly Kenton, MD
Phone: 312-926-7846
Click here to add this to my saved trials
