Magnetic Resonance Imaging (MRI) Solely For Liver Stereotactic Body Radiation Therapy (SBRT)



Status:Completed
Conditions:Liver Cancer, Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:21 - Any
Updated:4/7/2017
Start Date:August 2016
End Date:February 1, 2017

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This study is a research and development initiative established to explore the use of
magnetic resonance imaging (MRI) as a tool for managing organ motion of the liver in cancer
patients planning procedures for stereotactic body radiation therapy (SBRT).

There is a potential role to systematically implement MRI to establish appropriate workflow
of the implementation for tumor motion management in liver SBRT. Compared to CT, MRI has
many significant advantages for radiotherapy planning, including superior tumor and
soft-tissue contrast, flexible imaging orientation, freedom from radiation exposure and
real-time imaging. MRI solely based liver SBRT will allow for more precise delineation of
target volume, less uncertainties in treatment planning, better motion management, and
potentially better treatment outcome

Inclusion Criteria:

- Age ≥ 21

- Patients with primary stage I, II, III liver cancer or metastatic tumor in the liver
from any cancer site

- Signed, specific informed consent prior to study entry

- Women of child bearing potential must have a negative serum pregnancy test

Exclusion Criteria:

- Any condition for which a MRI procedure is contraindicated including presence of
metallic material in the body, such as pacemakers, non- MRI compatible surgical
clips, shrapnel.

- Pregnant or breast-feeding women are excluded.

- Subjects who have difficulty lying flat on their back for extended periods of time
We found this trial at
1
site
2301 Erwin Rd
Durham, North Carolina 27710
919-684-8111
Phone: 919-668-3726
Duke Univ Med Ctr As a world-class academic and health care system, Duke Medicine strives...
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Durham, NC
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