Trial of One Versus Two Doses of Dexamethasone for Pediatric Asthma Exacerbation
| Status: | Completed |
|---|---|
| Conditions: | Asthma |
| Therapuetic Areas: | Pulmonary / Respiratory Diseases |
| Healthy: | No |
| Age Range: | Any - 20 |
| Updated: | 3/1/2019 |
| Start Date: | November 2015 |
| End Date: | November 2017 |
A Randomized Double Blinded Placebo Controlled Trial of One Versus Two Doses of Oral Dexamethasone for the Treatment of Acute Asthma Exacerbation in the Pediatric Emergency Department (ED)
Comparing one versus two doses of oral dexamethasone for the treatment of asthma in the
pediatric emergency department.
pediatric emergency department.
A randomized double blinded placebo controlled trial comparing one dose of dexamethasone
administered in the Emergency Department with two doses, the first given in the emergency
department and the second 24 hours after the index ED visit.
administered in the Emergency Department with two doses, the first given in the emergency
department and the second 24 hours after the index ED visit.
Inclusion Criteria:
- History of asthma defined as at least two (2) prior episodes of respiratory illness
characterized by wheezing treated with inhaled beta agonists
Exclusion Criteria:
- pregnancy
- severe chronic cardiac, respiratory, neurological or neuromuscular disease
- complete resolution of symptoms after one treatment of beta agonists
- severe asthma symptoms as defined by a Pulmonary Index Score of 12 or greater
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New York Methodist Hospital A voluntary, acute-care teaching hospital, New York Methodist Hospital's mission is...
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