Evaluation of Patients With Known or Suspected Heart Disease



Status:Completed
Conditions:High Blood Pressure (Hypertension), Peripheral Vascular Disease, Cardiology, Cardiology, Cardiology, Cardiology, Cardiology, Nephrology
Therapuetic Areas:Cardiology / Vascular Diseases, Nephrology / Urology
Healthy:No
Age Range:Any
Updated:4/21/2016
Start Date:May 1992
End Date:January 2009

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Evaluation of Patients With Known or Suspected Heart Disease (Screening Protocol)

In this study researchers will admit and evaluate patients with known or suspected heart
disease referred to the Cardiology Branch of the National Heart, Lung, and Blood Institute
(NHLBI).

Patients participating in this study will undergo a general medical evaluation, including
blood tests, urine, examination, chest x-ray and electrocardiogram (EKG). In addition,
patients may be asked to have an echocardiogram (ultrasound scan of the heart) and to
perform an exercise stress test.

These tests are designed to assess the types and causes of patient's heart diseases and to
determine if they can participate in other, specific research studies.

The principal mission of the NIH is the conduct of research that elucidates biological
mechanisms, pathogenesis, and treatment of disease. Patients with known or suspected
cardiovascular diseases are referred to NHLBI cardiologists for consideration of
participation in clinical research protocols. However, eligibility for participation is
often uncertain from referral information or even after an outpatient evaluation. The
purpose of this protocol is to permit inpatient evaluation of patients for whom
participation in clinical research protocols is under consideration in order to determine
protocol eligibility by means of conventional laboratory and cardiovascular testing.

- INCLUSION CRITERIA:

The following is a representative list of the types of patient presentations and potential
diagnoses eligible for this protocol:

1. Coronary artery disease with angina or inducible myocardial ischemia as determined by
noninvasive testing.

2. Cardiomyopathies including congestive phenotypes.

3. Peripheral artery disease with intermittent claudication or limb-threatening
ischemia.

4. Renovascular disease with uncontrolled hypertension, intermittent pulmonary edema, or
evidence of ischemic nephropathy.

5. Upper extremity peripheral artery disease.

6. Diabetes with heart failure.

7. Pulmonary hypertension.

EXCLUSION CRITERIA:

Pregnancy, for those patients who require catheterization-based diagnostics.

Inability to provide informed consent.
We found this trial at
2
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9000 Rockville Pike
Bethesda, Maryland 20892
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8600 Old Georgetown Road
Bethesda, Maryland 20814
301-896-3100
Suburban Hospital Suburban Hospital is a community-based, not-for-profit hospital serving Montgomery County and the surrounding...
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