Gene Testing in Patients With Colon Cancer
| Status: | Completed |
|---|---|
| Conditions: | Colorectal Cancer, Colorectal Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 4/21/2016 |
| Start Date: | August 1998 |
| End Date: | January 2006 |
Tumor Replication Error (RER) Status and Outcome in a Colon Cancer Adjuvant Chemotherapy Trial
RATIONALE: Analyzing the structure of genes found in a person's cancer cells may help
doctors improve methods of treating patients with colon cancer.
PURPOSE: Clinical trial to study the genes of patients treated with chemotherapy for colon
cancer.
doctors improve methods of treating patients with colon cancer.
PURPOSE: Clinical trial to study the genes of patients treated with chemotherapy for colon
cancer.
OBJECTIVES:
- Determine the relationship between disease free survival, overall survival, and tumor
replication error status for patients who have received adjuvant chemotherapy for colon
cancer on CALGB protocol 8896.
- Determine the prognostic and predictive values for response to this therapy in these
patients.
- Determine the relationship between disease free survival, overall survival, and tumor
replication error status for patients who have received adjuvant chemotherapy for colon
cancer on CALGB protocol 8896.
- Determine the prognostic and predictive values for response to this therapy in these
patients.
DISEASE CHARACTERISTICS:
- Patients who received chemotherapy for colon cancer as part of CALGB protocol 8896
- Underwent an initial resection for adenocarcinoma of the colon and were determined to
have a high risk of tumor recurrence based upon nodal disease or local extension of
tumor with obstruction or perforation due to tumor
- Surgical specimen blocks available, including tumor tissue and normal tissue
We found this trial at
44
sites
Roswell Park Cancer Institute Welcome to Roswell Park Cancer Institute (RPCI), America's first cancer center...
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Duke Comprehensive Cancer Center Leading-edge cancer care and research have been a hallmark of Duke...
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200 Hawkins Drive
Iowa City, Iowa 52242
Iowa City, Iowa 52242
800-237-1225
Holden Comprehensive Cancer Center at University of Iowa Holden Comprehensive Cancer Center is dedicated to...
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CCOP - Mount Sinai Medical Center The Mount Sinai Community Clinical Oncology Program (MSCCOP) is...
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Rhode Island Hospital Founded in 1863, Rhode Island Hospital in Providence, RI, is a private,...
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Dana-Farber Cancer Institute Since it’s founding in 1947, Dana-Farber has been committed to providing adults...
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Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center — the world's oldest and...
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Univ of Nebraska Med Ctr A vital enterprise in the nation’s heartland, the University of...
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6900 Georgia Ave NW
Washington, District of Columbia 20307
Washington, District of Columbia 20307
(202) 782-6849
Walter Reed Army Medical Center The Walter Reed National Military Medical Center is one of...
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Medical Center Boulevard
Winston-Salem, North Carolina 27157
Winston-Salem, North Carolina 27157
336-716-2255
Comprehensive Cancer Center of Wake Forest University Our newly expanded Comprehensive Cancer Center is the...
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