Gene Testing in Patients With Colon Cancer
| Status: | Completed |
|---|---|
| Conditions: | Colorectal Cancer, Colorectal Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 4/21/2016 |
| Start Date: | August 1998 |
| End Date: | January 2006 |
Tumor Replication Error (RER) Status and Outcome in a Colon Cancer Adjuvant Chemotherapy Trial
RATIONALE: Analyzing the structure of genes found in a person's cancer cells may help
doctors improve methods of treating patients with colon cancer.
PURPOSE: Clinical trial to study the genes of patients treated with chemotherapy for colon
cancer.
doctors improve methods of treating patients with colon cancer.
PURPOSE: Clinical trial to study the genes of patients treated with chemotherapy for colon
cancer.
OBJECTIVES:
- Determine the relationship between disease free survival, overall survival, and tumor
replication error status for patients who have received adjuvant chemotherapy for colon
cancer on CALGB protocol 8896.
- Determine the prognostic and predictive values for response to this therapy in these
patients.
- Determine the relationship between disease free survival, overall survival, and tumor
replication error status for patients who have received adjuvant chemotherapy for colon
cancer on CALGB protocol 8896.
- Determine the prognostic and predictive values for response to this therapy in these
patients.
DISEASE CHARACTERISTICS:
- Patients who received chemotherapy for colon cancer as part of CALGB protocol 8896
- Underwent an initial resection for adenocarcinoma of the colon and were determined to
have a high risk of tumor recurrence based upon nodal disease or local extension of
tumor with obstruction or perforation due to tumor
- Surgical specimen blocks available, including tumor tissue and normal tissue
We found this trial at
44
sites
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Roswell Park Cancer Institute Welcome to Roswell Park Cancer Institute (RPCI), America's first cancer center...
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Duke Comprehensive Cancer Center Leading-edge cancer care and research have been a hallmark of Duke...
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200 Hawkins Drive
Iowa City, Iowa 52242
Iowa City, Iowa 52242
800-237-1225
Holden Comprehensive Cancer Center at University of Iowa Holden Comprehensive Cancer Center is dedicated to...
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CCOP - Mount Sinai Medical Center The Mount Sinai Community Clinical Oncology Program (MSCCOP) is...
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Rhode Island Hospital Founded in 1863, Rhode Island Hospital in Providence, RI, is a private,...
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Dana-Farber Cancer Institute Since it’s founding in 1947, Dana-Farber has been committed to providing adults...
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Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center — the world's oldest and...
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Univ of Nebraska Med Ctr A vital enterprise in the nation’s heartland, the University of...
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6900 Georgia Ave NW
Washington, District of Columbia 20307
Washington, District of Columbia 20307
(202) 782-6849
Walter Reed Army Medical Center The Walter Reed National Military Medical Center is one of...
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Medical Center Boulevard
Winston-Salem, North Carolina 27157
Winston-Salem, North Carolina 27157
336-716-2255
Comprehensive Cancer Center of Wake Forest University Our newly expanded Comprehensive Cancer Center is the...
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