Gene Testing in Patients With Colon Cancer



Status:Completed
Conditions:Colorectal Cancer, Colorectal Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:Any
Updated:4/21/2016
Start Date:August 1998
End Date:January 2006

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Tumor Replication Error (RER) Status and Outcome in a Colon Cancer Adjuvant Chemotherapy Trial

RATIONALE: Analyzing the structure of genes found in a person's cancer cells may help
doctors improve methods of treating patients with colon cancer.

PURPOSE: Clinical trial to study the genes of patients treated with chemotherapy for colon
cancer.

OBJECTIVES:

- Determine the relationship between disease free survival, overall survival, and tumor
replication error status for patients who have received adjuvant chemotherapy for colon
cancer on CALGB protocol 8896.

- Determine the prognostic and predictive values for response to this therapy in these
patients.

DISEASE CHARACTERISTICS:

- Patients who received chemotherapy for colon cancer as part of CALGB protocol 8896

- Underwent an initial resection for adenocarcinoma of the colon and were determined to
have a high risk of tumor recurrence based upon nodal disease or local extension of
tumor with obstruction or perforation due to tumor

- Surgical specimen blocks available, including tumor tissue and normal tissue
We found this trial at
44
sites
Medical Center Boulevard
Winston-Salem, North Carolina 27157
336-716-2255
Comprehensive Cancer Center of Wake Forest University Our newly expanded Comprehensive Cancer Center is the...
312
mi
from 43215
Winston-Salem, NC
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666 Elm Street
Buffalo, New York 14263
(716) 845-2300
Roswell Park Cancer Institute Welcome to Roswell Park Cancer Institute (RPCI), America's first cancer center...
295
mi
from 43215
Buffalo, NY
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125 Science Dr
Durham, North Carolina 27710
888.275.3853
Duke Comprehensive Cancer Center Leading-edge cancer care and research have been a hallmark of Duke...
354
mi
from 43215
Durham, NC
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200 Hawkins Drive
Iowa City, Iowa 52242
800-237-1225
Holden Comprehensive Cancer Center at University of Iowa Holden Comprehensive Cancer Center is dedicated to...
460
mi
from 43215
Iowa City, IA
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300 Community Drive
Manhasset, New York 11030
493
mi
from 43215
Manhasset, NY
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1331 Union Ave # 800
Memphis, Tennessee 38103
507
mi
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Memphis, TN
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4300 Alton Road
Miami Beach, Florida 33140
(305) 674-2625
CCOP - Mount Sinai Medical Center The Mount Sinai Community Clinical Oncology Program (MSCCOP) is...
991
mi
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Miami Beach, FL
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593 Eddy Street
Providence, Rhode Island 02903
401-444-4000
Rhode Island Hospital Founded in 1863, Rhode Island Hospital in Providence, RI, is a private,...
619
mi
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Providence, RI
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343
mi
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Baltimore, MD
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700 19th Street South
Birmingham, Alabama 35233
492
mi
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Birmingham, AL
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450 Brookline Ave
Boston, Massachusetts 2215
617-632-3000
Dana-Farber Cancer Institute Since it’s founding in 1947, Dana-Farber has been committed to providing adults...
643
mi
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Boston, MA
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299
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Buffalo, NY
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Chapel Hill, North Carolina 27599
353
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Chapel Hill, NC
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277
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Chicago, IL
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270
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Chicago, IL
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501
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Columbia, MO
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Columbia, Missouri 65203
501
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Columbia, MO
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2
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Columbus, OH
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Durham, North Carolina 27705
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Durham, NC
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1926
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La Jolla, CA
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Las Vegas, NV
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Lebanon, New Hampshire 03756
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Manhasset, NY
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Memphis, TN
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Minneapolis, Minnesota 55417
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Minneapolis, MN
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New York, NY
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New York, New York 10029
481
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New York, NY
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1275 York Ave
New York, New York 10021
(212) 639-2000
Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center — the world's oldest and...
480
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New York, NY
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Emile St
Omaha, Nebraska 68198
(402) 559-4000
Univ of Nebraska Med Ctr A vital enterprise in the nation’s heartland, the University of...
682
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Omaha, NE
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342
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Richmond, VA
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Richmond, Virginia 23298
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Richmond, VA
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Saint Louis, Missouri 63110
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Saint Louis, MO
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San Francisco, California 94121
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San Francisco, CA
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San Francisco, California 94143
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Syracuse, NY
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Syracuse, NY
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Syracuse, NY
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Togus, ME
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Washington, District of Columbia 20007
325
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Washington,
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6900 Georgia Ave NW
Washington, District of Columbia 20307
(202) 782-6849
Walter Reed Army Medical Center The Walter Reed National Military Medical Center is one of...
328
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Washington,
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White River Junction, Vermont 05009
606
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White River Junction, VT
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Wilmington, Delaware 19899
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Wilmington, DE
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Winston-Salem, North Carolina 27104
305
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Winston-Salem, NC
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607
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Worcester, MA
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