Child and Infant Learning Project



Status:Completed
Conditions:Other Indications, Neurology
Therapuetic Areas:Neurology, Other
Healthy:No
Age Range:Any - 7
Updated:4/21/2016
Start Date:September 2001
End Date:June 2015

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Neurobehavioral Correlates of Craniosynostosis

To learn more about the cognitive and motor development of infants and young children born
with a craniofacial defect called craniosynostosis.

In the first phase of this multi-site, 10-year longitudinal study, infants with one of four
types of single-suture craniosynostosis were recruited: sagittal, metopic, right unilateral
coronal, and left unilateral coronal. A case-matched "control" group of healthy, normal
infants was also followed. This study, which is now in its second phase, is following this
same cohort of children at the age of 7 years.

Enrollment criteria at Phase 1:

- Confirmed diagnosis of single-suture, nonsyndromic craniosynostosis (sagittal,
metopic, unilateral coronal, or lambdoid)

- Corrective (cranioplastic) surgery not yet performed

- Child born at 34 weeks gestation or later

- Absence of neurological conditions/significant health problems

- 33 months or younger at time of enrollment (male or female).

Enrollment criteria at Phase 2:

All participants enrolled in phase 1 are invited to participate in phase 2.
We found this trial at
4
sites
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mi
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St. Louis, MO
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Atlanta, Georgia 30342
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mi
from
Atlanta, GA
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4800 Sand Point Way NE
Seattle, Washington 98105
(206) 987-2000
Seattle Children's Hospital Seattle Children’s Hospital specializes in meeting the unique physical, emotional and developmental...
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mi
from
Seattle, WA
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mi
from
Westchester, IL
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