Novel Epothilone Plus Capecitabine Versus Capecitabine Alone in Patients With Advanced Breast Cancer



Status:Completed
Conditions:Breast Cancer, Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:4/21/2016
Start Date:September 2003
End Date:March 2008

Use our guide to learn which trials are right for you!

Trial Summary
Trial Overview
Inclusion Criteria

A Phase III Trial of Novel Epothilone BMS-247550 Plus Capecitabine Versus Capecitabine Alone in Patients With Advanced Breast Cancer Previously Treated With or Resistant to an Anthracycline and Who Are Taxane Resistant

The purpose of this clinical research study is to learn if BMS-247550 added to the approved
therapy of capecitabine is better than capecitabine alone in shrinking or slowing the growth
of the cancer in women with metastatic breast cancer who are resistant to taxane and
received anthracycline chemotherapy. The safety of this treatment will also be studied.


- Patients must have received either 2 or 3 prior chemotherapy regimens including
adjuvant or neoadjuvant therapy.

- Prior treatment must have included both an anthracycline (i.e., doxorubicin or
epirubicin) and a taxane (i.e., paclitaxel or docetaxel).

- Patients must have received a minimum cumulative dose of anthracycline or must be
resistant to an anthracycline.

- Patients must be resistant to taxane therapy.

- Patients may not have any history of brain and/or leptomeningeal metastases.

- Patients may not have CTC Grade 2 or greater neuropathy (motor or sensory).

- Patients may have not have had prior treatment with an epothilone and/or capecitabine
(i.e., Xeloda)
We found this trial at
33
sites
Local Institution
Baltimore, Maryland 21237
?
mi
from
Baltimore, MD
Click here to add this to my saved trials
Local Institution
Albuquerque, New Mexico 87108
?
mi
from
Albuquerque, NM
Click here to add this to my saved trials
Local Institution
Austin, Texas 78701
?
mi
from
Austin, TX
Click here to add this to my saved trials
Local Institution
Burlington, Massachusetts
?
mi
from
Burlington, MA
Click here to add this to my saved trials
Local Institution
Burlington, Vermont
?
mi
from
Burlington, VT
Click here to add this to my saved trials
Local Institution
Capital Federal, Buenos Aires
?
mi
from
Capital Federal,
Click here to add this to my saved trials
Local Institution
Columbia, Missouri 65212
?
mi
from
Columbia, MO
Click here to add this to my saved trials
Local Institution
Columbia, South Carolina 29201
?
mi
from
Columbia, SC
Click here to add this to my saved trials
Local Institution
Columbus, Ohio 43219
?
mi
from
Columbus, OH
Click here to add this to my saved trials
Local Institution
Denver, Colorado 80220
?
mi
from
Denver, CO
Click here to add this to my saved trials
Local Institution
Greenville, South Carolina 29615
?
mi
from
Greenville, SC
Click here to add this to my saved trials
Local Institution
Hartford, Connecticut 06106
?
mi
from
Hartford, CT
Click here to add this to my saved trials
Local Institution
Houston, Texas 77030
?
mi
from
Houston, TX
Click here to add this to my saved trials
Local Institution
Jackson, Mississippi 39216
?
mi
from
Jackson, MS
Click here to add this to my saved trials
Local Institution
Kansas City, Missouri 64108
?
mi
from
Kansas City, MO
Click here to add this to my saved trials
Local Institution
Knoxville, Tennessee 37920
?
mi
from
Knoxville, TN
Click here to add this to my saved trials
Local Institution
Little Rock, Arkansas 72201
?
mi
from
Little Rock, AR
Click here to add this to my saved trials
Local Institution
Livingston, New Jersey 07039
?
mi
from
Livingston, NJ
Click here to add this to my saved trials
Local Institution
Morgantown, West Virginia 26505
?
mi
from
Morgantown, WV
Click here to add this to my saved trials
Local Institution
Nashville, Tennessee 37203
?
mi
from
Nashville, TN
Click here to add this to my saved trials
Local Institution
New Brunswick, New Jersey 08901
?
mi
from
New Brunswick, NJ
Click here to add this to my saved trials
Local Institution
New York, New York 10016
?
mi
from
New York, NY
Click here to add this to my saved trials
Local Institution
Ogden, Utah
?
mi
from
Ogden, UT
Click here to add this to my saved trials
Local Institution
Oklahoma City, Oklahoma 73103
?
mi
from
Oklahoma City, OK
Click here to add this to my saved trials
Local Institution
Omaha, Nebraska 68114
?
mi
from
Omaha, NE
Click here to add this to my saved trials
Local Institution
Orlando, Florida 32803
?
mi
from
Orlando, FL
Click here to add this to my saved trials
Local Institution
Pittsburgh, Pennsylvania 15240
?
mi
from
Pittsburgh, PA
Click here to add this to my saved trials
Local Institution
Saint Louis, Missouri 63104
?
mi
from
Saint Louis, MO
Click here to add this to my saved trials
Local Institution
San Francisco, California 94107
?
mi
from
San Francisco, CA
Click here to add this to my saved trials
Local Institution
Tacoma, Washington
?
mi
from
Tacoma, WA
Click here to add this to my saved trials
Local Institution
Tulsa, Oklahoma 74136
?
mi
from
Tulsa, OK
Click here to add this to my saved trials
Local Institution
Vallejo, California 94589
?
mi
from
Vallejo, CA
Click here to add this to my saved trials
Local Institution
Washington, District of Columbia 20010
?
mi
from
Washington,
Click here to add this to my saved trials