The Biology of Claudin 3 in Primary Human Mammary Epithelial Cell Culture
| Status: | Recruiting |
|---|---|
| Conditions: | Breast Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 3/30/2013 |
| Start Date: | May 2007 |
The objective of the present study is to determine whether or not primary human mammary
epithelial cells are competent for use in molecular studies of transepithelial
electrophysiology focusing on the function of the tight junction protein claudin 3.
Human breast Tissue will be removed from mastectomy specimens and used as a source to
generate epithelial cells for study.
Inclusion Criteria:
- Subjects of this pilot study are limited to those female patients who are undergoing
therapeutic or prophylactic mastectomy procedures conducted by the department of
Surgery at HUMC.
Exclusion Criteria:
- From within this population, no exclusion criteria shall be applied based on age,
race, ethnicity, gender, HIV status, or menopause.
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