Greenwich Lumbar Stenosis SLIP Study
| Status: | Completed |
|---|---|
| Conditions: | Orthopedic, Orthopedic |
| Therapuetic Areas: | Orthopedics / Podiatry |
| Healthy: | No |
| Age Range: | 50 - 80 |
| Updated: | 4/21/2016 |
| Start Date: | May 2002 |
| End Date: | October 2014 |
Greenwich Lumbar Stenosis SLIP Study: A Multi-center, Randomized, Prospective Clinical Trial Comparing Spinal Laminectomy to Laminectomy With Instrumented Pedicle Screw Fusion for Lumbar Stenosis With Grade I Spondylolisthesis
The purpose of the study is to determine the proper use of lower back screws and rods
(instrumentation) and bony fusion in subjects with one level of degenerative spinal
narrowing (stenosis) compressing nerves to the legs with one spinal bone slipping forward on
another (spondylolisthesis). There are two types of operations that surgeons perform for
this problem. Some spinal surgeons remove some bone in the back (laminectomy) to decompress
the nerves. Other surgeons perform a laminectomy (decompression) as above, but feel that it
is also important to strengthen the back by placing screws and rods into the spine and
adding more bone to obtain a new bridge of bone away from the nerves (decompression with
instrumented fusion). This study aims to test the hypothesis that adding instrumented fusion
to a decompression for this spinal problem will improve long term patient outcomes.
(instrumentation) and bony fusion in subjects with one level of degenerative spinal
narrowing (stenosis) compressing nerves to the legs with one spinal bone slipping forward on
another (spondylolisthesis). There are two types of operations that surgeons perform for
this problem. Some spinal surgeons remove some bone in the back (laminectomy) to decompress
the nerves. Other surgeons perform a laminectomy (decompression) as above, but feel that it
is also important to strengthen the back by placing screws and rods into the spine and
adding more bone to obtain a new bridge of bone away from the nerves (decompression with
instrumented fusion). This study aims to test the hypothesis that adding instrumented fusion
to a decompression for this spinal problem will improve long term patient outcomes.
There is considerable debate among spinal surgeons regarding the optimal surgical procedure
for lumbar spinal stenosis with a grade I spondylolisthesis. The major question is whether
or not instrumented pedicle screw fusion should be undertaken when a decompressive
laminectomy is performed to relieve neural compression. This multi-center, randomized,
prospective clinical study aims to address this question by testing the hypothesis that
adding instrumented fusion to a decompression for this spinal problem will improve long-term
patient outcomes.
for lumbar spinal stenosis with a grade I spondylolisthesis. The major question is whether
or not instrumented pedicle screw fusion should be undertaken when a decompressive
laminectomy is performed to relieve neural compression. This multi-center, randomized,
prospective clinical study aims to address this question by testing the hypothesis that
adding instrumented fusion to a decompression for this spinal problem will improve long-term
patient outcomes.
Inclusion Criteria:
- Symptomatic lumbar spinal stenosis and single level grade I spondylolisthesis (3-14
mm)
Exclusion Criteria:
- History of previous lumbar spinal surgery in region of stenosis
- Gross spinal instability (defined as greater than 3 mm motion on flexion/extension
studies)
- Serious medical illness (ASA Class III or higher)
- Spondylolisthesis greater than 14 mm or associated with spondylolysis
We found this trial at
5
sites
Click here to add this to my saved trials
Click here to add this to my saved trials
Rhode Island Hospital Founded in 1863, Rhode Island Hospital in Providence, RI, is a private,...
Click here to add this to my saved trials
Lahey Clinic When Frank Lahey, MD, founded a group practice in 1923, his vision was...
Click here to add this to my saved trials
Click here to add this to my saved trials