Study of Erbitux™ (Cetuximab) in Pediatric Patients With Refractory Solid Tumors



Status:Completed
Conditions:Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:1 - 18
Updated:4/21/2016
Start Date:August 2005
End Date:March 2008

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Phase I Study of Erbitux™ (Cetuximab) in Pediatric Patients With Refractory Solid Tumors

The purpose of this clinical research study is to establish the maximum tolerated dose and
recommended Phase II dose of Erbitux™ in combination with Irinotecan in pediatric and
adolescent patients with refractory solid tumors.


Inclusion Criteria:

- Histologically or cytologically confirmed diagnosis of a solid tumor which has
progressed on, or following standard therapy, or for which no standard effective
therapy is known.

- Children age 1-18 years.

Exclusion Criteria:

- Presence of active infection.

- Requirement to receive concurrent chemotherapy immunotherapy, radiotherapy, or any
other investigational drug while on study.

- Inadequate bone marrow, hepatic, or renal function.
We found this trial at
9
sites
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Baltimore, MD
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Gainesville, Florida 32610
(352) 392-3261
University of Florida The University of Florida (UF) is a major, public, comprehensive, land-grant, research...
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Gainesville, FL
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1405 Clifton Road NE
Atlanta, Georgia 30322
404-785-6000
Children's Healthcare of Atlanta Whether treating a toddler in an emergency or supporting a teen...
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Atlanta, GA
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Denver, Colorado 80218
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Denver, CO
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1515 Holcombe Blvd
Houston, Texas 77030
 713-792-2121
University of Texas M.D. Anderson Cancer Center The mission of The University of Texas MD...
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mi
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Houston, TX
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from
Nashville, TN
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1275 York Ave
New York, New York 10021
(212) 639-2000
Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center — the world's oldest and...
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from
New York, NY
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1919 E Thomas Rd
Phoenix, Arizona 85006
(602) 933-1000
Phoenix Children's Hospital Phoenix Children's Hospital has provided hope, healing, and the best healthcare for...
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mi
from
Phoenix, AZ
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1295 North Martin Avenue
Tucson, Arizona 85721
(520) 626-1197
University of Arizona Health Sciences Center The Arizona Health Sciences Center (AHSC) at the University...
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mi
from
Tucson, AZ
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