An Intervention Trial for Cardiac Neuropathy in Type 1 Diabetes
| Status: | Completed |
|---|---|
| Conditions: | Diabetic Neuropathy, Neurology |
| Therapuetic Areas: | Endocrinology, Neurology |
| Healthy: | No |
| Age Range: | 18 - 65 |
| Updated: | 4/21/2016 |
| Start Date: | January 2000 |
| End Date: | December 2009 |
Oxidative Stress and Cardiovascular Denervation in Diabetes: An Interventional Trial
The focus of this project is cardiovascular diabetic autonomic neuropathy (DAN). DAN affects
the nerves that control heart rate and blood flow to the heart in people with diabetes. DAN
may cause problems with the rhythm of the heartbeat or decrease blood flow to the heart.
Three medications will be tested for their effectiveness in DAN.
the nerves that control heart rate and blood flow to the heart in people with diabetes. DAN
may cause problems with the rhythm of the heartbeat or decrease blood flow to the heart.
Three medications will be tested for their effectiveness in DAN.
Inclusion Criteria:
- Type 1 diabetes
- A1C <9%
- Mild neuropathy
- Mild retinopathy
- Mild nephropathy
Exclusion Criteria:
- History of drug or alcohol dependence, heart disease, viral illness, liver disease,
advanced kidney disease
- Pregnant or nursing
- Severely overweight
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University of Michigan The University of Michigan was founded in 1817 as one of the...
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