Radiation-Induced Cytokine Cascades and Their Correlation With Central Nervous System Injury
| Status: | Completed |
|---|---|
| Conditions: | Brain Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 4/21/2016 |
| Start Date: | November 1999 |
Treatment for brain cancer may include radiation therapy. Radiation therapy is the treatment
of tumors with X-rays. This study is related to understanding the side effects of radiation
treatment for brain tumors.
This study is being conducted by the University of Rochester Cancer Center to compare the
extent of side effects of brain cancer treatment with changes in levels of blood proteins
called cytokines.
of tumors with X-rays. This study is related to understanding the side effects of radiation
treatment for brain tumors.
This study is being conducted by the University of Rochester Cancer Center to compare the
extent of side effects of brain cancer treatment with changes in levels of blood proteins
called cytokines.
Inclusion Criteria:
- Any patient who will be treated to the brain or spinal axis for a CNS tum Patients so
treated will be stratified according to whether or not the hypo is included in the
treatment fields.
- Patients receiving external beam radiation to the brain may also be rece chemotherapy
or interferon-beta. (Add. #1, 11-9-95)
- Patients receiving high dose rate (stereotactic radiosurgery) are eligible.
- Patients must sign a study specific informed consent meeting all federal a
guidelines.
- Patients of any age, including children, are eligible (Add. #3, 11/25/97).
Exclusion Criteria:
- Patients who have a malignancy involving the hypothalamic-pituitary ax
- Patients who are not treated with irradiation to the brain or spinal axis.
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