Wireless Capsule Endoscopy in Small-Bowel Crohn's Disease

Wireless capsule endoscopy (CE) is a Food and Drug Administration (FDA) approved technology
that allows viewing of the entire small-bowel. Capsule endoscopy involves swallowing a
pill-sized camera that sends images to a data recorder worn on a vest. Because Crohn's
disease (CD) often involves the small bowel, we would like to find out if capsule endoscopy
is useful in diagnosing small-bowel Crohn's disease. Current methods for diagnosing
small-bowel Crohn's disease include colonoscopy, esophagogastroduodenoscopy (EGD),
enteroscopy (ENT), single contrast barium small-bowel follow through (SBFT), and double
contrast small-bowel enteroclysis (SBE), but these tests are unable to identify the presence
or extent of small-bowel disease in many patients.

Inclusion Criteria:

- English speaking adult patients (>18 years old) with known Crohn's disease

Exclusion Criteria:

- Severe medical or psychiatric co-morbidities

- Active swallowing problems

- Bowel obstruction

- History of stricture or fistula

- Pregnancy

- Taking aspirin/non-steroidal anti-inflammatory drug (NSAID) or potassium chloride
(KCl) within 4 weeks prior to the colonoscopy and anytime after colonoscopy

- Inability to consent

- Exclusion of patients whose colonoscopy was done for reasons other than
signs/symptoms suggestive of Crohn's disease