DHA Supplementation and Pregnancy Outcome



Status:Completed
Conditions:Women's Studies
Therapuetic Areas:Reproductive
Healthy:No
Age Range:16 - 36
Updated:4/21/2016
Start Date:January 2006
End Date:October 2011

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Kansas University DHA Outcome Study (KUDOS)

The purpose of the study is to determine if increasing DHA intake during pregnancy can
increase gestation duration and enhance infant and childhood outcomes related to visual
acuity, stereoacuity, attention, and distractibility.

Although numerous trials show benefits of postnatal DHA supplementation for visual acuity
and others show benefits for cognitive function and/or attention, studies of increased DHA
exposure during fetal life are needed, especially in the US. Women in the US consume low
amounts of DHA compared to other world populations, and this likely means less DHA transfer
to the fetus than in many other populations. Prenatal DHA exposure may be more important
than postnatal exposure, because animal studies show critical windows for brain DHA
accumulation in relation to effects on neurotransmitters such as serotonin, dopamine and
GABA.

Inclusion Criteria:

- Pregnant 8-20 wks at enrollment

- single fetus

- BMI <40

Exclusion Criteria:

- diabetes (Type I, ii, GDM)

- hypertension (primary, PIH, preeclampsia/eclampsia)
We found this trial at
2
sites
2301 Holmes
Kansas City, Missouri 64108
816-404-1000
Truman Medical Center Located in the heart of downtown Kansas City, TMC Hospital Hill is...
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Kansas City, MO
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3901 Rainbow Blvd
Kansas City, Kansas 66160
(913) 588-5000
University of Kansas Medical Center The University of Kansas Medical Center serves Kansas through excellence...
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Kansas City, KS
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