Antibiotic Resistant Community-Acquired E. Coli

The following variables will be followed: age, sex, hospital location at the time of
positive culture (ER, medical ward, ICU etc), prior hospitalization or nursing home
admission, receipt of outpatient dialysis or other regular medical care (eg, outpatient
chemotherapy), presence of invasive devices, receipt of antibiotics, including their type
and whether they were adequate for the resistance profile of the organism, prior positive
microbiologic cultures.

Inclusion Criteria:

- ll patients with E. coli infections during the time period of the study will be
reviewed. A community-associated E. coli isolate will be defined as one which was
recovered from a clinical culture from a patient at UPMC-P who had no established
risk factors for infection with an antibiotic resistant organism.

Established risk factors are defined as:

- Isolation of the organism two or more days after admission for hospitalization OR A
history of hospitalization, surgery, dialysis, or residence in a long-term care
facility within one year before the culture date

- OR The presence of an indwelling catheter or percutaneous medical device (eg,
tracheostomy tube, gastrostomy tube, or Foley catheter) at the time of the culture

- OR Previous isolation of an antibiotic resistant organism