Identification of Gene and Protein Markers of Kidney Injury in Aminoglycoside-treated Children
| Status: | Completed |
|---|---|
| Conditions: | Renal Impairment / Chronic Kidney Disease, Infectious Disease |
| Therapuetic Areas: | Immunology / Infectious Diseases, Nephrology / Urology |
| Healthy: | No |
| Age Range: | Any - 18 |
| Updated: | 4/21/2016 |
| Start Date: | June 2006 |
| End Date: | December 2010 |
Assessment of Gene and Urinary Protein Expression in Aminoglycoside-treated and Untreated Infants, Children and Adolescents
The purposes of this study are to identify potential gene and protein markers of
aminoglycoside-induced kidney injury in infants, children and adolescents treated with
aminoglycoside antibiotics.
aminoglycoside-induced kidney injury in infants, children and adolescents treated with
aminoglycoside antibiotics.
Inclusion Criteria: (1) Hospitalized male and female newborns, infants, children and
adolescents (ages birth to 18 years) with a diagnosis of suspected or proven bacterial
sepsis, meningitis or other indication necessitating aminoglycoside therapy (2)
hospitalized and outpatient newborns, infants, children and adolescents (ages birth to 18
years) who are not receiving aminoglycoside therapy.
Exclusion Criteria: (1) Current treatment with inhaled or ophthalmic aminoglycosides (2)
Prior treatment with an aminoglycoside within the last 30 days
We found this trial at
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Virginia Commonwealth University Since our founding as a medical school in 1838, Virginia Commonwealth University...
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