Efficacy Trial Comparing ZD6474 With Erlotinib in NSCLC After Failure of at Least One Prior Chemotherapy



Status:Completed
Conditions:Lung Cancer, Lung Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:1/27/2018
Start Date:August 2006
End Date:November 2016

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Trial Summary
Trial Overview
Inclusion Criteria

A Phase III, International, Randomised, Double Blind, Parallel-Group Study to Assess the Efficacy of Zactima™ Versus Tarceva® in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer After Failure of at Least One Prior Chemotherapy

To determine if ZD6474 a new investigational drug, is effective in treating Non Small Lung
Cancer and if so, how it compares with another type of anti cancer therapy chemotherapy,
Erlotinib


Inclusion Criteria:

- Confirmed locally advanced or metastatic NSCLC

- Failure of at least one but not more than two prior chemotherapy regimens

Exclusion Criteria:

- Prior treatment with erlotinib (Tarceva), gefitinib (IRESSA), sunitinib (Sutent),
sorafenib (Nexavar)

- Chemotherapy or other type of anti cancer therapy within 4 weeks of study start
We found this trial at
30
sites
Clinical Trial Facility in Ciudad de Buenos Aires
Ciudad de Buenos Aires,
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Ciudad de Buenos Aires,
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Clinical Trial Facility in Amarillo Texas
Amarillo, Texas
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Amarillo, TX
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Clinical Trial Facility in Baltimore Maryland
Baltimore, Maryland
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Baltimore, MD
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Clinical Trial Facility in Berkeley California
Berkeley, California 94704
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Berkeley, CA
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Clinical Trial Facility in Boynton Beach Florida
Boynton Beach, Florida 33472
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Boynton Beach, FL
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Clinical Trial Facility in Burien Washington
Burien, Washington 98166
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Burien, WA
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Clinical Trial Facility in Canton Ohio
Canton, Ohio 44718
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Canton, OH
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Clinical Trial Facility in Chattanooga Tennessee
Chattanooga, Tennessee
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Chattanooga, TN
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Clinical Trial Facility in Cincinnati Ohio
Cincinnati, Ohio
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Cincinnati, OH
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Clinical Trial Facility in Columbia Missouri
Columbia, Missouri 65201
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Columbia, MO
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Clinical Trial Facility in Fairfax Virginia
Fairfax, Virginia 22031
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Fairfax, VA
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Clinical Trial Facility in Fort Myers Florida
Fort Myers, Florida 33916
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Fort Myers, FL
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Clinical Trial Facility in Garland Texas
Garland, Texas 75042
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Garland, TX
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Clinical Trial Facility in Greenville South Carolina
Greenville, South Carolina 29605
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Greenville, SC
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Clinical Trial Facility in Hickory North Carolina
Hickory, North Carolina 28601
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Hickory, NC
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Clinical Trial Facility in Jacksonville Florida
Jacksonville, Florida 32209
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Jacksonville, FL
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Clinical Trial Facility in Latham New York
Latham, New York 12110
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Latham, NY
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Clinical Trial Facility in Lexington Kentucky
Lexington, Kentucky
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Lexington, KY
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Clinical Trial Facility in Los Angeles California
Los Angeles, California
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Los Angeles, CA
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Clinical Trial Facility in Louisville Kentucky
Louisville, Kentucky 40202
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Louisville, KY
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Clinical Trial Facility in Metairie Louisiana
Metairie, Louisiana 70006
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Metairie, LA
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Clinical Trial Facility in Nashville Tennessee
Nashville, Tennessee 37232
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Nashville, TN
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Clinical Trial Facility in Norfolk Virginia
Norfolk, Virginia 23507
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Norfolk, VA
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Clinical Trial Facility in Port Saint Lucie Florida
Port Saint Lucie, Florida
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Port Saint Lucie, FL
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Clinical Trial Facility in Richmond Virginia
Richmond, Virginia 23227
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Richmond, VA
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Clinical Trial Facility in Saint Louis Missouri
Saint Louis, Missouri 63110
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Saint Louis, MO
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Clinical Trial Facility in Santa Rosa California
Santa Rosa, California 95405
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Santa Rosa, CA
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Clinical Trial Facility in Webster Texas
Webster, Texas 77598
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Webster, TX
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Clinical Trial Facility in Wichita Kansas
Wichita, Kansas 67214
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Wichita, KS
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Clinical Trial Facility in Yakima Washington
Yakima, Washington 98902
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Yakima, WA
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