Lifetime Risk for Cardiovascular Disease Among Non-White Ethnic Groups



Status:Completed
Conditions:Atrial Fibrillation, Peripheral Vascular Disease, Peripheral Vascular Disease, Cardiology, Cardiology
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - Any
Updated:4/21/2016
Start Date:July 2006
End Date:July 2006

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Epidemiologic Study of Ethnicity and Lifetime Risks for Cardiovascular Disease

Cardiovascular disease (CVD) is one of the leading causes of death in the United States.
Currently, there is little information about the lifetime risk of CVD among non-white ethnic
groups. This study will analyze data from participants in several ongoing clinical studies
to identify the lifetime risk for CVD among various ethnicities.

CVD affects millions of people in the United States. Current treatment guidelines for CVD
take into account an individual's risk of developing the disease within 10 years; the
intensity of therapy is usually matched to the 10-year risk magnitude. However, many
individuals have a low 10-year risk of CVD, but have an elevated lifetime risk of developing
the disease. Unfortunately, few studies have examined the lifetime risks for CVD, and these
studies have been almost exclusively performed in the Caucasian population. There have been
no studies that focus on the lifetime risks for CVD among other ethnic groups. Because the
incidence of CVD and other causes of death vary among different ethnic groups, it is
important to examine each group separately. Using data from ongoing clinical studies, this
study will evaluate the lifetime risks for CVD among different ethnic groups. The results
from this study will assist in estimating the future incidence of CVD among ethnic groups,
improving risk communication within patient care, and identifying new populations of
individuals at risk for CVD.

This study will use previously collected data on 500,000 individuals participating in
pre-specified clinical studies. Some of the participating studies include the following:
Atherosclerosis Risk in Communities, Framingham Heart, Honolulu Heart, Puerto Rico Heart
Health, Coronary Artery Risk Development in Young Adults (CARDIA), Cardiovascular Health,
Chicago Heart Association Detection Project in Industry, Women's Health Initiative
Observational Studies, and Multiple Risk Factor Intervention Trial (MRFIT). There will be no
study visits specifically for this study. Researchers will collect information on CVD risk
factors and demographics, including sex, race, and age; they will then compare this
information to overall survival, CVD associated survival, and lifetime risk for CVD.

Inclusion Criteria:

- Participating in a specified epidemiologic study

Exclusion Criteria:

- Pre-existing CVD prior to study entry
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