A Study Using Intravitreal Injections of a Small Interfering RNA in Patients With Age-Related Macular Degeneration
| Status: | Terminated |
|---|---|
| Conditions: | Cardiology, Ocular |
| Therapuetic Areas: | Cardiology / Vascular Diseases, Ophthalmology |
| Healthy: | No |
| Age Range: | 50 - Any |
| Updated: | 4/21/2016 |
| Start Date: | January 2007 |
| End Date: | February 2009 |
This is a 24-month study to evaluate multiple doses of AGN211745 (previously known as
Sirna-027) in treatment of subfoveal choroidal neovascularization associated with
age-related macular degeneration
Sirna-027) in treatment of subfoveal choroidal neovascularization associated with
age-related macular degeneration
Inclusion Criteria:
- 50 years or older with "wet" AMD as determined by an ophthalmologist
- decrease in visual acuity (20/40 to 20/640) in at least one eye
Exclusion Criteria:
- Uncontrolled systemic disease
- History of heart attack or stroke within one year of study entry
- Symptomatic coronary artery disease
- Cataracts that interfere with vision
We found this trial at
2
sites
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