Study of Mental Fatigue in Polio Survivors
| Status: | Recruiting |
|---|---|
| Conditions: | Infectious Disease |
| Therapuetic Areas: | Immunology / Infectious Diseases |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/2/2016 |
| Contact: | Sandra Maxwell, RN |
| Email: | smaxwell@usuhs.edu |
| Phone: | 301-9840400 |
Post-Poliomyelitis Syndrome (PPS) is the term describing the new problems affecting polio
survivors many years after recovery from paralytic polio. Among the symptoms, fatigue is one
of the most frequent and debilitating. In addition to physical incapacitation, the fatigue
of PPS also affects mental function. The term “brain fatigue” is usually used by patients to
express problems on the areas of attention, concentration, memory and clear thinking.
Unfortunately, little is known about cognitive fatigue of PPS patients. This study is meant
to examine if mental impairment is present in PPS patients and, if so, how it interferes on
the self-function of patients. Patients will undergo an interview, clinical and neurological
evaluation, and a battery of screening laboratory tests to make sure they are eligible for
the study. Patients who qualify will undergo neuropsychometric tests in order to assay
performance in the main areas of cognitive functioning. Through this organized approach we
expect to be able to determine if mental fatigue is a significant problem affecting polio
survivors, what areas are most affected, and how it may interfere with daily living.
survivors many years after recovery from paralytic polio. Among the symptoms, fatigue is one
of the most frequent and debilitating. In addition to physical incapacitation, the fatigue
of PPS also affects mental function. The term “brain fatigue” is usually used by patients to
express problems on the areas of attention, concentration, memory and clear thinking.
Unfortunately, little is known about cognitive fatigue of PPS patients. This study is meant
to examine if mental impairment is present in PPS patients and, if so, how it interferes on
the self-function of patients. Patients will undergo an interview, clinical and neurological
evaluation, and a battery of screening laboratory tests to make sure they are eligible for
the study. Patients who qualify will undergo neuropsychometric tests in order to assay
performance in the main areas of cognitive functioning. Through this organized approach we
expect to be able to determine if mental fatigue is a significant problem affecting polio
survivors, what areas are most affected, and how it may interfere with daily living.
Inclusion Criteria:
- 18 years of age or older
- Be a survivor of poliomyelitis
- Willing to attend two clinic visits for completion of screening procedures and
required tests
Exclusion Criteria:
- Suffer from medical conditions that can interfere with cognitive function, including
stroke, traumatic brain injury, dementia (progressive memory loss), severe
depression, psychosis or other psychiatric disorders, etc.
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