An Investigational Study Drug, Palbociclib (PD-0332991), Is Being Studied In Patients With Mantle Cell Lymphoma. Patients Must Have Received Prior Treatment(s) For Mantle Cell Lymphoma.
| Status: | Completed |
|---|---|
| Conditions: | Lymphoma |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - 99 |
| Updated: | 4/21/2016 |
| Start Date: | May 2007 |
| End Date: | March 2012 |
A Pilot Study Of Pd 0332991 In Patients With Previously Treated Mantle Cell Lymphoma
This is a pilot study evaluating tumor activity using Positron Emission Tomography, which is
also known as a "PET scan". This study will assess the safety of using PD-0332991 in
patients with mantle cell lymphoma.
also known as a "PET scan". This study will assess the safety of using PD-0332991 in
patients with mantle cell lymphoma.
Inclusion Criteria:
- Histologically documented MCL.
- Must have received at least one prior therapy.
- Eastern Cooperative Oncology Group (ECOG) performance status ≤1.
- Adequate organ function as outlined in the protocol.
Exclusion Criteria:
- Major surgery, radiation therapy, or systemic therapy within 4 weeks of study
enrollment.
- Prior radiation therapy to >25% of the bone marrow (whole pelvis is 25%).
- Uncontrolled brain metastases, spinal cord compression, carcinomatous meningitis, or
leptomeningeal disease.
We found this trial at
6
sites
Brigham and Women's Hosp Boston’s Brigham and Women’s Hospital (BWH) is an international leader in...
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Dana-Farber Cancer Institute Since it’s founding in 1947, Dana-Farber has been committed to providing adults...
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Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center — the world's oldest and...
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New York, New York 10021
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