A Study to Evaluate the Effectiveness of Voriconazole + Micafungin Versus Voriconazole Alone for Invasive Aspergillosis



Status:Withdrawn
Conditions:Pulmonary
Therapuetic Areas:Pulmonary / Respiratory Diseases
Healthy:No
Age Range:2 - Any
Updated:4/21/2016
Start Date:February 2007

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Trial Summary
Trial Overview
Inclusion Criteria

A Double-Blind, Randomized Controlled Trial of Voriconazole (VFEND®) Plus Micafungin (MYCAMINE™) Versus Voriconazole Plus Placebo in the Treatment of Patients With Proven or Probable Invasive Aspergillosis

To evaluate the therapeutic effectiveness of voriconazole + micafungin versus voriconazole
alone as primary therapy for invasive aspergillosis.


Inclusion Criteria:

- Proven, probable or possible invasive aspergillosis

- Patient is 2 years of age or older

Exclusion Criteria:

- The patient has been administered an antifungal agent (voriconazole, itraconazole,
posaconazole, caspofungin, micafungin, anidulafungin, amphotericin B, or lipid
formulation of amphotericin B) for >7 days immediately prior to randomization for
treatment of the Possible, Probable, or Proven invasive aspergillosis for which the
patient is being enrolled.

- The patient has been treated with voriconazole for > 7 days immediately prior to
randomization
We found this trial at
44
sites
Clinical Trial Facility in Portland Oregon
Portland, Oregon
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Clinical Trial Facility in Akron Ohio
Akron, Ohio
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Akron, OH
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Clinical Trial Facility in Albany New York
Albany, New York 12205
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Albany, NY
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Clinical Trial Facility in Ann Arbor Michigan
Ann Arbor, Michigan 48109
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Ann Arbor, MI
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Clinical Trial Facility in Atlanta Georgia
Atlanta, Georgia
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Atlanta, GA
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Clinical Trial Facility in Baltimore Maryland
Baltimore, Maryland
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Baltimore, MD
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Clinical Trial Facility in Beech Grove Indiana
Beech Grove, Indiana
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Beech Grove, IN
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Clinical Trial Facility in Bethesda Maryland
Bethesda, Maryland
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Bethesda, MD
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Clinical Trial Facility in Birmingham Alabama
Birmingham, Alabama
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Birmingham, AL
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Clinical Trial Facility in Boston Massachusetts
Boston, Massachusetts
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Boston, MA
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Clinical Trial Facility in Charlestown Massachusetts
Charlestown, Massachusetts
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Charlestown, MA
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Clinical Trial Facility in Charlottesville Virginia
Charlottesville, Virginia
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Charlottesville, VA
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Clinical Trial Facility in Chicago Illinois
Chicago, Illinois
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Chicago, IL
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Clinical Trial Facility in Cincinnati Ohio
Cincinnati, Ohio
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Cincinnati, OH
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Clinical Trial Facility in Columbus Ohio
Columbus, Ohio 43214
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Columbus, OH
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Clinical Trial Facility in Dallas Texas
Dallas, Texas 75390
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Dallas, TX
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Clinical Trial Facility in Denver Colorado
Denver, Colorado
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Denver, CO
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Clinical Trial Facility in Detroit Michigan
Detroit, Michigan
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Detroit, MI
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Clinical Trial Facility in Fairfax Virginia
Fairfax, Virginia 22031
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Fairfax, VA
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Clinical Trial Facility in Fountain Valley California
Fountain Valley, California 92708
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Fountain Valley, CA
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Clinical Trial Facility in Grand Rapids Michigan
Grand Rapids, Michigan 49503
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Grand Rapids, MI
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Clinical Trial Facility in Houston Texas
Houston, Texas
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Houston, TX
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Clinical Trial Facility in Indianapolis Indiana
Indianapolis, Indiana 46202
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Indianapolis, IN
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Clinical Trial Facility in Kansas City Kansas
Kansas City, Kansas
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Kansas City, KS
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Clinical Trial Facility in Lexington Kentucky
Lexington, Kentucky
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Lexington, KY
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Clinical Trial Facility in Los Angeles California
Los Angeles, California
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Los Angeles, CA
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Clinical Trial Facility in Madison Wisconsin
Madison, Wisconsin 53792
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Madison, WI
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Clinical Trial Facility in Miami Florida
Miami, Florida 33136
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Miami, FL
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Clinical Trial Facility in Minneapolis Minnesota
Minneapolis, Minnesota 55455
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Minneapolis, MN
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Clinical Trial Facility in New York New York
New York, New York 10032
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New York, NY
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Clinical Trial Facility in Omaha Nebraska
Omaha, Nebraska
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Omaha, NE
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Clinical Trial Facility in Palo Alto California
Palo Alto, California 94301
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Palo Alto, CA
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Clinical Trial Facility in Philadelphia Pennsylvania
Philadelphia, Pennsylvania
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Philadelphia, PA
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Clinical Trial Facility in Pittsburgh Pennsylvania
Pittsburgh, Pennsylvania
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Pittsburgh, PA
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Clinical Trial Facility in Richmond Virginia
Richmond, Virginia 23227
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Richmond, VA
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Clinical Trial Facility in Rochester Minnesota
Rochester, Minnesota 55905
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Rochester, MN
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Clinical Trial Facility in Rochester New York
Rochester, New York
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Rochester, NY
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Clinical Trial Facility in Sacramento California
Sacramento, California 95825
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Sacramento, CA
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Clinical Trial Facility in San Antonio Texas
San Antonio, Texas 78224
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San Antonio, TX
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Clinical Trial Facility in San Francisco California
San Francisco, California
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Clinical Trial Facility in Washington District of Columbia
Washington, District of Columbia
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Washington,
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Clinical Trial Facility in Wichita Kansas
Wichita, Kansas 67214
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Wichita, KS
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Clinical Trial Facility in Winston-Salem North Carolina
Winston-Salem, North Carolina
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Winston-Salem, NC
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Clinical Trial Facility in Worcester Massachusetts
Worcester, Massachusetts 01655
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Worcester, MA
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