A Study of the Interaction of Rifampin and Vinflunine in Subjects With Advanced Cancer
| Status: | Withdrawn |
|---|---|
| Conditions: | Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/21/2016 |
| Start Date: | September 2007 |
| End Date: | November 2008 |
Effect of Rifampin on the Pharmacokinetics of Intravenous (IV) Vinflunine in Subjects With Advanced Cancer
The purpose of this study is to test how vinflunine interacts with rifampin in the human
body
body
Inclusion Criteria:
- Cancer unresponsive to previous treatment
- Consent for genetic samples
Exclusion Criteria:
- Cancer of the blood
- Spread of cancer to the brain
- Moderate or severe nerve damage
- Low white blood cell counts and platelet counts
- Inadequate liver or kidney function
- Prior treatment with vinflunine
- Use of certain medications that might interfere with the metabolism of vinflunine
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