A Pilot Study of Functional Optical Coherence Tomography for Ocular Imaging



Status:Completed
Conditions:Ocular, Ocular, Diabetes
Therapuetic Areas:Endocrinology, Ophthalmology
Healthy:No
Age Range:18 - Any
Updated:4/21/2016
Start Date:January 2007
End Date:July 2013

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Growing evidence shows that altered blood flow plays a major role in many vision-threatening
diseases including glaucoma, diabetic retinopathy, age-related macular degeneration, Central
Retinal Vein Occlusion, and Branch Retinal Vein Occlusion. Optical coherence tomography, an
established imaging technique use for eye exam in clinical ophthalmology, provides
high-resolution cross sectional images of the retina and has increased our ability to
understand many eye diseases.

Optical Coherence Tomography is a non-invasive technique use a broadband light source to
illuminate the area of study with light in the near infrared spectrum, then obtains static
images of tissue structure from interference signals of the back-reflected light.

Optical Coherence Tomography a non-contact, non-invasive means of documenting both tissue
structure and blood flow changes in ocular disease and can provide high resolution
cross-sectional images of tissue structure, direct visualization of blood flow in blood
vessels of the eye.

Inclusion Criteria:

- Adult 18 years and older with normal eye, or has been diagnosed with eye disease.

Exclusion Criteria:

- Less than 18 years of age.
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